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Synthesis of α-CF3-substituted γ,δ-didehydro lysine derivatives

, 
Daria Vladimirovna Vorobyeva 1
Daria Vladimirovna Vorobyeva
,  , 
Arthur Karenovich Mailyan 1
Arthur Karenovich Mailyan
,  , 
Sergey Nikolaevich Osipov 1
Sergey Nikolaevich Osipov
10.1016/j.mencom.2022.03.036
Published 2022-03-06
Communication , Volume 32, Issue 2, 260-261
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Philippova A. N. et al. Synthesis of α-CF3-substituted γ,δ-didehydro lysine derivatives // Mendeleev Communications. 2022. Vol. 32. No. 2. pp. 260-261.
GOST all authors (up to 50) Copy
Philippova A. N., Vorobyeva D. V., Vasilyeva T. P., Mailyan A. K., Gribanov P. S., Osipov S. N. Synthesis of α-CF3-substituted γ,δ-didehydro lysine derivatives // Mendeleev Communications. 2022. Vol. 32. No. 2. pp. 260-261.
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TY - JOUR
DO - 10.1016/j.mencom.2022.03.036
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.03.036
TI - Synthesis of α-CF3-substituted γ,δ-didehydro lysine derivatives
T2 - Mendeleev Communications
AU - Philippova, Anna Nikolaevna
AU - Vorobyeva, Daria Vladimirovna
AU - Vasilyeva, Tamara Petrovna
AU - Mailyan, Arthur Karenovich
AU - Gribanov, Pavel Sergeevich
AU - Osipov, Sergey Nikolaevich
PY - 2022
DA - 2022/03/06
PB - Mendeleev Communications
SP - 260-261
IS - 2
VL - 32
ER -
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@article{2022_Philippova,
author = {Anna Nikolaevna Philippova and Daria Vladimirovna Vorobyeva and Tamara Petrovna Vasilyeva and Arthur Karenovich Mailyan and Pavel Sergeevich Gribanov and Sergey Nikolaevich Osipov},
title = {Synthesis of α-CF3-substituted γ,δ-didehydro lysine derivatives},
journal = {Mendeleev Communications},
year = {2022},
volume = {32},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.03.036},
number = {2},
pages = {260--261},
doi = {10.1016/j.mencom.2022.03.036}
}
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Philippova, Anna Nikolaevna, et al. “Synthesis of α-CF3-substituted γ,δ-didehydro lysine derivatives.” Mendeleev Communications, vol. 32, no. 2, Mar. 2022, pp. 260-261. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.03.036.
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Keywords

$\alpha$-amino phosphonates
$\gamma$,$\delta$-didehydro lysine
hydrogenation
Mannich reaction
α-amino carboxylates

Abstract

An efficient and selective access to novel α-CF3-substituted γ,δ-didehydro lysine derivatives and their phosphorus analogues has been developed via the Cu-catalyzed Mannich reaction of α-amino α-propargyl α-trifluoromethyl carboxylates or phosphonates with different secondary amines and paraformaldehyde.

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