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Novel mucoadhesive carriers based on alginate-acrylamide hydrogels for drug delivery

Marina Yur`evna Gorshkova 1
Marina Yur`evna Gorshkova
, 
Ludmila Vital'evna Vanchugova 1
Ludmila Vital'evna Vanchugova
, 
Irina Fedorovna Volkova 1
Irina Fedorovna Volkova
, 
Irina Vasil'evna Obydennova 1
Irina Vasil'evna Obydennova
, 
Ivan L'vovich Valuev 1
Ivan L'vovich Valuev
, 
Lev Ivanovich Valuev 1
Lev Ivanovich Valuev
10.1016/j.mencom.2022.03.012
Published 2022-03-06
Communication , Volume 32, Issue 2, 189-191
12
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Gorshkova M. Y. et al. Novel mucoadhesive carriers based on alginate-acrylamide hydrogels for drug delivery // Mendeleev Communications. 2022. Vol. 32. No. 2. pp. 189-191.
GOST all authors (up to 50) Copy
Gorshkova M. Y., Vanchugova L. V., Volkova I. F., Obydennova I. V., Valuev I. L., Valuev L. I. Novel mucoadhesive carriers based on alginate-acrylamide hydrogels for drug delivery // Mendeleev Communications. 2022. Vol. 32. No. 2. pp. 189-191.
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TY - JOUR
DO - 10.1016/j.mencom.2022.03.012
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.03.012
TI - Novel mucoadhesive carriers based on alginate-acrylamide hydrogels for drug delivery
T2 - Mendeleev Communications
AU - Gorshkova, Marina Yur`evna
AU - Vanchugova, Ludmila Vital'evna
AU - Volkova, Irina Fedorovna
AU - Obydennova, Irina Vasil'evna
AU - Valuev, Ivan L'vovich
AU - Valuev, Lev Ivanovich
PY - 2022
DA - 2022/03/06
PB - Mendeleev Communications
SP - 189-191
IS - 2
VL - 32
ER -
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@article{2022_Gorshkova,
author = {Marina Yur`evna Gorshkova and Ludmila Vital'evna Vanchugova and Irina Fedorovna Volkova and Irina Vasil'evna Obydennova and Ivan L'vovich Valuev and Lev Ivanovich Valuev},
title = {Novel mucoadhesive carriers based on alginate-acrylamide hydrogels for drug delivery},
journal = {Mendeleev Communications},
year = {2022},
volume = {32},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.03.012},
number = {2},
pages = {189--191},
doi = {10.1016/j.mencom.2022.03.012}
}
MLA
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Gorshkova, Marina Yur`evna, et al. “Novel mucoadhesive carriers based on alginate-acrylamide hydrogels for drug delivery.” Mendeleev Communications, vol. 32, no. 2, Mar. 2022, pp. 189-191. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2022.03.012.

Keywords

covalent network
drug delivery system
interpenetrating networks
ionic network
N-diethylacrylamide)
poly(N
polyacrylamide
sodium alginate
two-component hydrogel

Abstract

New mucoadhesive two-component carriers for drug delivery based on synthetic acrylamide/diethylacrylamide and natural alginate hydrogels have been synthesized. The introduction of sodium alginate into polyacrylamide/ poly(diethylacrylamide) gels, followed by their crosslinking with metal ions, significantly changed structure and properties of hydrogels, such as swelling degree, drug capacity and drug release rate in physiological solution. The structure of the gels was characterized by FTIR spectroscopy and scanning electron microscopy.

References

2.
pH Sensitive Hydrogels in Drug Delivery: Brief History, Properties, Swelling, and Release Mechanism, Material Selection and Applications
Rizwan M., Yahya R., Hassan A., Yar M., Azzahari A., Selvanathan V., Sonsudin F., Abouloula C.
Polymers, 2017
4.
Alginate microparticles as oral colon drug delivery device: A review
Agüero L., Zaldivar-Silva D., Peña L., Dias M.L.
Carbohydrate Polymers, 2017
5.
Fundamental Concepts of Hydrogels: Synthesis, Properties, and Their Applications
Bashir S., Hina M., Iqbal J., Rajpar A.H., Mujtaba M.A., Alghamdi N.A., Wageh S., Ramesh K., Ramesh S.
Polymers, 2020
7.
Injectable Hydrogels for Cancer Therapy over the Last Decade
Cirillo, Curcio, Nicoletta, Iemma
Pharmaceutics, 2019
8.
Timaeva O.I., Pashkin I.I., Kuz’micheva G.M., Sadovskaya N.V.
Mendeleev Communications, 2019
9.
Dolinina E.S., Kraev A.S., Parfenyuk E.V.
Mendeleev Communications, 2020
10.
Sodium alginate and carbopol microcapsules: preparation, polyphenol encapsulation and release efficiency
Popova E.V., Morozova P.V., Uspenskaya M.V., Radilov A.S.
Russian Chemical Bulletin, 2021
11.
Mucoadhesive Polymer Carriers of Intranasal Medicines
Valuev I.L., Gorshkova M.Y., Vanchugova L.V., Valuev L.I.
Polymer Science - Series A, 2019
12.
Sodium Alginate Based Mucoadhesive Hydrogels
Gorshkova M.Y., Volkova I.F., Vanchugova L.V., Valuev I.L., Valuev L.I.
Applied Biochemistry and Microbiology, 2019
13.
Self-assembled stable sponge-type nanocarries for Brucea javanica oil delivery.
Zou A., Li Y., Chen Y., Angelova A., Garamus V.M., Li N., Drechsler M., Angelov B., Gong Y.
Colloids and Surfaces B: Biointerfaces, 2017
14.
Spiridonov V.V., Afanasov M.I., Makarova L.A., Sybachin A.V., Yaroslavov A.A.
Mendeleev Communications, 2021
15.
Magnetically Sensitive Alginate-Templated Polyelectrolyte Multilayer Microcapsules for Controlled Release of Doxorubicin
Liu J., Zhang Y., Wang C., Xu R., Chen Z., Gu N.
Journal of Physical Chemistry C, 2010
16.
A novel role for lidocaine in COVID-19 patients?
Finnerty D.T., Buggy D.J.
British Journal of Anaesthesia, 2020
17.
Nebulized Lidocaine in COVID-19, An Hypothesis
Ali Z.A., El-Mallakh R.S.
Medical Hypotheses, 2020
20.
Mechanical properties of interpenetrating polymer network hydrogels based on hybrid ionically and covalently crosslinked networks
Naficy S., Kawakami S., Sadegholvaad S., Wakisaka M., Spinks G.M.
Journal of Applied Polymer Science, 2013
22.
Poly(N,N′-Diethylacrylamide)-Based Thermoresponsive Hydrogels with Double Network Structure
Hanyková L., Krakovský I., Šestáková E., Šťastná J., Labuta J.
Polymers, 2020
24.
Evaluation of Novel Antibiotic-Eluting Thermoresponsive Chitosan-PDEAAm Based Wound Dressings
Ngadaonye J.I., Geever L.M., McEvoy K.E., Killion J., Brady D.B., Higginbotham C.L.
International Journal of Polymeric Materials and Polymeric Biomaterials, 2014
27.
10.1016/j.mencom.2022.03.012_b0135
Lebedeva
Polym. Sci., Ser. A, 2000
28.
10.1016/j.mencom.2022.03.012_b0140
Feldstein
Polym. Sci., Ser. A, 1999
29.
10.1016/j.mencom.2022.03.012_b0145
Bellamy
The Infrared Spectra of Complex Molecules, 1954