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One-pot synthesis of α-trifluoromethylstyrenes from aryl ketones and the Ruppert–Prakash reagent

Vitalij Vladimirovich Levin 1
Vitalij Vladimirovich Levin
, 
10.1016/j.mencom.2021.09.030
Published 2021-09-08
Communication , Volume 31, Issue 5, 684-685
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Levin V. V., Dilman A. D. One-pot synthesis of α-trifluoromethylstyrenes from aryl ketones and the Ruppert–Prakash reagent // Mendeleev Communications. 2021. Vol. 31. No. 5. pp. 684-685.
GOST all authors (up to 50) Copy
Levin V. V., Dilman A. D. One-pot synthesis of α-trifluoromethylstyrenes from aryl ketones and the Ruppert–Prakash reagent // Mendeleev Communications. 2021. Vol. 31. No. 5. pp. 684-685.
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TY - JOUR
DO - 10.1016/j.mencom.2021.09.030
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.09.030
TI - One-pot synthesis of α-trifluoromethylstyrenes from aryl ketones and the Ruppert–Prakash reagent
T2 - Mendeleev Communications
AU - Levin, Vitalij Vladimirovich
AU - Dilman, Alexander Davidovich
PY - 2021
DA - 2021/09/08
PB - Mendeleev Communications
SP - 684-685
IS - 5
VL - 31
ER -
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@article{2021_Levin,
author = {Vitalij Vladimirovich Levin and Alexander Davidovich Dilman},
title = {One-pot synthesis of α-trifluoromethylstyrenes from aryl ketones and the Ruppert–Prakash reagent},
journal = {Mendeleev Communications},
year = {2021},
volume = {31},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.09.030},
number = {5},
pages = {684--685},
doi = {10.1016/j.mencom.2021.09.030}
}
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Levin, Vitalij Vladimirovich, and Alexander Davidovich Dilman. “One-pot synthesis of α-trifluoromethylstyrenes from aryl ketones and the Ruppert–Prakash reagent.” Mendeleev Communications, vol. 31, no. 5, Sep. 2021, pp. 684-685. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.09.030.

Keywords

alkenes
Ketones
organofluorine compounds
silicon reagents
trifluoromethylation

Abstract

A new synthesis of α-trifluoromethylstyrenes from aromatic ketones and (trifluoromethyl) trimethylsilane is described. The reaction involves nucleophilic trifluoromethylation and elimination of trimethylsilanol, which are performed within one reaction flask.

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