Home / Publications / Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents

Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents

, 
Kamilla Gulamovna Aminulla 1
Kamilla Gulamovna Aminulla
, 
Viatcheslav Nikolaevich Azev 2
Viatcheslav Nikolaevich Azev
, 
Tatiana Mikhailovna Kulinich 3
Tatiana Mikhailovna Kulinich
, 
Vladislav Aleksandrovich Vasilichin 1
Vladislav Aleksandrovich Vasilichin
, 
A A Shtil 1, 4
A A Shtil
, 
Tatyana Aleksandrovna Podrugina 1
Tatyana Aleksandrovna Podrugina
10.1016/j.mencom.2021.09.008
Published 2021-09-08
Communication , Volume 31, Issue 5, 615-617
12
Share
Cite this
GOST
 | 
Cite this
GOST Copy
Doroshenko I. A. et al. Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents // Mendeleev Communications. 2021. Vol. 31. No. 5. pp. 615-617.
GOST all authors (up to 50) Copy
Doroshenko I. A., Aminulla K. G., Azev V. N., Kulinich T. M., Vasilichin V. A., Shtil A. A., Podrugina T. A. Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents // Mendeleev Communications. 2021. Vol. 31. No. 5. pp. 615-617.
RIS
 | 
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.mencom.2021.09.008
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.09.008
TI - Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents
T2 - Mendeleev Communications
AU - Doroshenko, Irina Andreevna
AU - Aminulla, Kamilla Gulamovna
AU - Azev, Viatcheslav Nikolaevich
AU - Kulinich, Tatiana Mikhailovna
AU - Vasilichin, Vladislav Aleksandrovich
AU - Shtil, A A
AU - Podrugina, Tatyana Aleksandrovna
PY - 2021
DA - 2021/09/08
PB - Mendeleev Communications
SP - 615-617
IS - 5
VL - 31
ER -
BibTex
 | 
Cite this
BibTex (up to 50 authors) Copy
@article{2021_Doroshenko,
author = {Irina Andreevna Doroshenko and Kamilla Gulamovna Aminulla and Viatcheslav Nikolaevich Azev and Tatiana Mikhailovna Kulinich and Vladislav Aleksandrovich Vasilichin and A A Shtil and Tatyana Aleksandrovna Podrugina},
title = {Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents},
journal = {Mendeleev Communications},
year = {2021},
volume = {31},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.09.008},
number = {5},
pages = {615--617},
doi = {10.1016/j.mencom.2021.09.008}
}
MLA
Cite this
MLA Copy
Doroshenko, Irina Andreevna, et al. “Synthesis of modified conformationally fixed tricarbocyanine dyes for conjugation with therapeutic agents.” Mendeleev Communications, vol. 31, no. 5, Sep. 2021, pp. 615-617. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.09.008.

Keywords

cell-penetrating peptides
conjugates
fluorescent markers
fluorophores
tricarbocyanine dyes
β-alanine

Abstract

New β-alanine modified tricarbocyanines containing various substituents at quaternized nitrogen atoms were obtained. The peptide synthesis method has been utilized for further conjugation thus giving promising tricarbocyanines containing two sulfonate groups and total negative charge of the fluorophore.

References

1.
Heptamethine Cyanine Dye Mediated Drug Delivery: Hype or Hope
Choi P.J., Park T.I., Cooper E., Dragunow M., Denny W.A., Jose J.
Bioconjugate Chemistry, 2020
2.
10.1016/j.mencom.2021.09.008_b0010
Chambre
Bioconjugate Chem., 1885
3.
Rational Design and Synthesis of a Metalloproteinase-Activatable Probe for Dual-Modality Imaging of Metastatic Lymph Nodes in Vivo
Yin L., Sun H., Zhao M., Wang A., Qiu S., Gao Y., Ding J., Ji S., Shi H., Gao M.
Journal of Organic Chemistry, 2019
5.
Sensory effects of fluorescent organic dyes
Traven V.F., Cheptsov D.A.
Russian Chemical Reviews, 2020
6.
Red Light-Initiated Cross-Linking of NIR Probes to Cytoplasmic RNA: An Innovative Strategy for Prolonged Imaging and Unexpected Tumor Suppression
Ye S., Cui C., Cheng X., Zhao M., Mao Q., Zhang Y., Wang A., Fang J., Zhao Y., Shi H.
Journal of the American Chemical Society, 2020
7.
Novel therapeutic interventions in cancer treatment using protein and peptide-based targeted smart systems
Zafar S., Beg S., Panda S.K., Rahman M., Alharbi K.S., Jain G.K., Ahmad F.J.
Seminars in Cancer Biology, 2021
10.
Mechanism Matters: A Taxonomy of Cell Penetrating Peptides
Kauffman W.B., Fuselier T., He J., Wimley W.C.
Trends in Biochemical Sciences, 2015
12.
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
Wender P.A., Mitchell D.J., Pattabiraman K., Pelkey E.T., Steinman L., Rothbard J.B.
Proceedings of the National Academy of Sciences of the United States of America, 2000
14.
10.1016/j.mencom.2021.09.008_b0070
Cano-Cortes
Nanomedicine, 2020
15.
Controllable Self‐Assembly of Peptide‐Cyanine Conjugates In Vivo as Fine‐Tunable Theranostics
Zheng R., Yang J., Mamuti M., Hou D., An H., Zhao Y., Wang H.
Angewandte Chemie - International Edition, 2021
16.
Synthesis of advanced fluorescent probes — water-soluble symmetrical tricarbocyanines with phosphonate groups
Podrugina T.A., Temnov V.V., Doroshenko I.A., Kuzmin V.A., Nekipelova T.D., Proskurnina M.V., Zefirov N.S.
Russian Chemical Bulletin, 2016
17.
Explorations into the Effect of meso ‐Substituents in Tricarbocyanine Dyes: A Path to Diverse Biomolecular Probes and Materials
Exner R.M., Cortezon‐Tamarit F., Pascu S.I.
Angewandte Chemie - International Edition, 2020
18.
Synthesis and photophysical properties of conformationally fixed tricarbocyanines with phosphonate groups
Podrugina T.A., Pavlova A.S., Doroshenko I.A., Kuz’min V.A., Kostyukov A.A., Shtil’ A.A.
Russian Chemical Bulletin, 2018
21.
Molecular Design Strategies for Near-Infrared Ratiometric Fluorescent Probes Based on the Unique Spectral Properties of Aminocyanines
Kiyose K., Aizawa S., Sasaki E., Kojima H., Hanaoka K., Terai T., Urano Y., Nagano T.
Chemistry - A European Journal, 2009