Home / Publications / High antibacterial activity and low toxicity of pyridoxal derivatives of chitosan and their nanoparticles

High antibacterial activity and low toxicity of pyridoxal derivatives of chitosan and their nanoparticles

Andreii Sergeevich Kritchenkov 1, 2
Andreii Sergeevich Kritchenkov
, 
Margarita Nikolaevna Kurasova 1
Margarita Nikolaevna Kurasova
, 
Anastasia Andreevna Godzishevskaya 1
Anastasia Andreevna Godzishevskaya
, 
Elizaveta Sergeevna Mitrofanova 1
Elizaveta Sergeevna Mitrofanova
, 
Anton Romanovich Egorov 1
Anton Romanovich Egorov
, 
Niyaz Zakievich Yagafarov 1, 3
Niyaz Zakievich Yagafarov
, 
Moises J Ballesteros Meza 1
Moises J Ballesteros Meza
, 
Alexander G Tskhovrebov 1
Alexander G Tskhovrebov
, 
Alexey Antonovich Artemjev 1
Alexey Antonovich Artemjev
, 
Elena Vladimirovna Andrusenko 4
Elena Vladimirovna Andrusenko
, 
Victor Nikolaevich Khrustalev 1, 5
Victor Nikolaevich Khrustalev
10.1016/j.mencom.2021.07.022
Published 2021-07-07
Communication , Volume 31, Issue 4, 504-506
12
Share
Cite this
GOST
 | 
Cite this
GOST Copy
Kritchenkov A. S. et al. High antibacterial activity and low toxicity of pyridoxal derivatives of chitosan and their nanoparticles // Mendeleev Communications. 2021. Vol. 31. No. 4. pp. 504-506.
GOST all authors (up to 50) Copy
Kritchenkov A. S., Kurasova M. N., Godzishevskaya A. A., Mitrofanova E. S., Egorov A. R., Yagafarov N. Z., Ballesteros Meza M. J., Tskhovrebov A. G., Artemjev A. A., Andrusenko E. V., Khrustalev V. N. High antibacterial activity and low toxicity of pyridoxal derivatives of chitosan and their nanoparticles // Mendeleev Communications. 2021. Vol. 31. No. 4. pp. 504-506.
RIS
 | 
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.mencom.2021.07.022
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.07.022
TI - High antibacterial activity and low toxicity of pyridoxal derivatives of chitosan and their nanoparticles
T2 - Mendeleev Communications
AU - Kritchenkov, Andreii Sergeevich
AU - Kurasova, Margarita Nikolaevna
AU - Godzishevskaya, Anastasia Andreevna
AU - Mitrofanova, Elizaveta Sergeevna
AU - Egorov, Anton Romanovich
AU - Yagafarov, Niyaz Zakievich
AU - Ballesteros Meza, Moises J
AU - Tskhovrebov, Alexander G
AU - Artemjev, Alexey Antonovich
AU - Andrusenko, Elena Vladimirovna
AU - Khrustalev, Victor Nikolaevich
PY - 2021
DA - 2021/07/07
PB - Mendeleev Communications
SP - 504-506
IS - 4
VL - 31
ER -
BibTex
 | 
Cite this
BibTex (up to 50 authors) Copy
@article{2021_Kritchenkov,
author = {Andreii Sergeevich Kritchenkov and Margarita Nikolaevna Kurasova and Anastasia Andreevna Godzishevskaya and Elizaveta Sergeevna Mitrofanova and Anton Romanovich Egorov and Niyaz Zakievich Yagafarov and Moises J Ballesteros Meza and Alexander G Tskhovrebov and Alexey Antonovich Artemjev and Elena Vladimirovna Andrusenko and Victor Nikolaevich Khrustalev},
title = {High antibacterial activity and low toxicity of pyridoxal derivatives of chitosan and their nanoparticles},
journal = {Mendeleev Communications},
year = {2021},
volume = {31},
publisher = {Mendeleev Communications},
month = {Jul},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.07.022},
number = {4},
pages = {504--506},
doi = {10.1016/j.mencom.2021.07.022}
}
MLA
Cite this
MLA Copy
Kritchenkov, Andreii Sergeevich, et al. “High antibacterial activity and low toxicity of pyridoxal derivatives of chitosan and their nanoparticles.” Mendeleev Communications, vol. 31, no. 4, Jul. 2021, pp. 504-506. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.07.022.

Keywords

Antibacterial activity
chitosan
low toxicity
nanoparticles
pyridoxal

Abstract

The pyridoxal derivatives of chitosan with various degrees of substitution (DS) were synthesized from low-, moderate- and high-molecular-weight chitosans by their reaction with pyridoxal followed by treatment with NaBH4. The derivative of moderate molecular weight and high DS demonstrated a maximum antibacterial activity against S. aureus and E. coli. The nanoparticles of this derivative obtained by ionic gelation are nontoxic, and they exhibit a high in vitro antibacterial effect, which slightly exceeds that of ampicillin and gentamicin.

References

1.
10.1016/j.mencom.2021.07.022_b0005
Najafpour
Chem. Biochem. Eng. Q., 2012
2.
Polyethylene materials with multifunctional surface properties by electrospraying chitosan/vitamin E formulation destined to biomedical and food packaging applications
Stoleru E., Munteanu S.B., Dumitriu R.P., Coroaba A., Drobotă M., Zemljic L.F., Pricope G.M., Vasile C.
Iranian Polymer Journal (English Edition), 2016
3.
Development of red apple pomace extract/chitosan-based films reinforced by TiO2 nanoparticles as a multifunctional packaging material
Lan W., Wang S., Zhang Z., Liang X., Liu X., Zhang J.
International Journal of Biological Macromolecules, 2021
4.
Biocompatible AIE material from natural resources: Chitosan and its multifunctional applications
Dong Z., Cui H., Wang Y., Wang C., Li Y., Wang C.
Carbohydrate Polymers, 2020
5.
A novel design and synthesis of multifunctional magnetic chitosan microsphere based on phase change materials
Chen X., Zhao Y., Zhang Y., Lu A., Li X., Liu L., Qin G., Fang Z., Zhang J., Liu Y.
Materials Letters, 2019
6.
Multifunctional zirconium oxide doped chitosan based hybrid nanocomposites as bone tissue engineering materials
Bhowmick A., Jana P., Pramanik N., Mitra T., Banerjee S.L., Gnanamani A., Das M., Kundu P.P.
Carbohydrate Polymers, 2016
9.
Ultrasound-assisted catalyst-free phenol-yne reaction for the synthesis of new water-soluble chitosan derivatives and their nanoparticles with enhanced antibacterial properties
Kritchenkov A.S., Egorov A.R., Volkova O.V., Kritchenkov I.S., Kurliuk A.V., Shakola T.V., Khrustalev V.N.
International Journal of Biological Macromolecules, 2019
10.
Kritchenkov A.S., Kurachenkov A.I., Egorov A.R., Yagafarov N.Z., Fortalnova E.A., Lobanov N.N., Dysin A.P., Khomik A.S., Khrustalev V.N.
Mendeleev Communications, 2020
11.
Antibacterial Activity of Chitosan Nanoparticles: A Review
Chandrasekaran M., Kim K.D., Chun S.C.
Processes, 2020