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Synthesis and cytotoxic activity of new annulated furazan derivatives

Elena Borisovna Rakhimova 1
Elena Borisovna Rakhimova
,  , 
Ekaterina Sergeevna Meshcheryakova 1
Ekaterina Sergeevna Meshcheryakova
, 
Lilya Useinovna Dzhemileva 1
Lilya Useinovna Dzhemileva
, 
Vladimir Anatol'evich D'yakonov 1
Vladimir Anatol'evich D'yakonov
, 
Askhat Gabdrakhmanovich Ibragimov 1
Askhat Gabdrakhmanovich Ibragimov
, 
10.1016/j.mencom.2021.04.026
Published 2021-04-28
Communication , Volume 31, Issue 3, 362-364
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Rakhimova E. B. et al. Synthesis and cytotoxic activity of new annulated furazan derivatives // Mendeleev Communications. 2021. Vol. 31. No. 3. pp. 362-364.
GOST all authors (up to 50) Copy
Rakhimova E. B., Kirsanov V. Y., Meshcheryakova E. S., Dzhemileva L. U., D'yakonov V. A., Ibragimov A. G., Dzhemilev U. M. Synthesis and cytotoxic activity of new annulated furazan derivatives // Mendeleev Communications. 2021. Vol. 31. No. 3. pp. 362-364.
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TY - JOUR
DO - 10.1016/j.mencom.2021.04.026
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.04.026
TI - Synthesis and cytotoxic activity of new annulated furazan derivatives
T2 - Mendeleev Communications
AU - Rakhimova, Elena Borisovna
AU - Kirsanov, Victor Yuryevich
AU - Meshcheryakova, Ekaterina Sergeevna
AU - Dzhemileva, Lilya Useinovna
AU - D'yakonov, Vladimir Anatol'evich
AU - Ibragimov, Askhat Gabdrakhmanovich
AU - Dzhemilev, Usein Memetovich
PY - 2021
DA - 2021/04/28
PB - Mendeleev Communications
SP - 362-364
IS - 3
VL - 31
ER -
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@article{2021_Rakhimova,
author = {Elena Borisovna Rakhimova and Victor Yuryevich Kirsanov and Ekaterina Sergeevna Meshcheryakova and Lilya Useinovna Dzhemileva and Vladimir Anatol'evich D'yakonov and Askhat Gabdrakhmanovich Ibragimov and Usein Memetovich Dzhemilev},
title = {Synthesis and cytotoxic activity of new annulated furazan derivatives},
journal = {Mendeleev Communications},
year = {2021},
volume = {31},
publisher = {Mendeleev Communications},
month = {Apr},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.04.026},
number = {3},
pages = {362--364},
doi = {10.1016/j.mencom.2021.04.026}
}
MLA
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MLA Copy
Rakhimova, Elena Borisovna, et al. “Synthesis and cytotoxic activity of new annulated furazan derivatives.” Mendeleev Communications, vol. 31, no. 3, Apr. 2021, pp. 362-364. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.04.026.

Keywords

5,11-dioxa-2,3a,4,6,6b,8,9a,10,12,12bdecaazadicyclopenta[e,l]pyrenes
aminals
aza-acetalization
Brønsted acids
cytotoxic activity
furazans
heterocyclization
Polycycles

Abstract

New 2,8-di(het)aryl-containing dioxadecaazadicyclopenta[e,l]pyrenes, furazan-annulated polyaza polycycles, have been synthesized by acid-catalyzed cyclocondensation of difurazanotetraazadecalin with formaldehyde and primary (het)arylamines. The cytotoxic activity of these compounds against tumor cell lines (Jurkat, K562, U937, HL60) has been estimated.

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