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Reaction of Reformatsky reagents with 2,5-diphenyl-1,3,4-oxadiazole

Elena Aleksandrovna Nikiforova 1
Elena Aleksandrovna Nikiforova
, 
Nikolai Fedorovich Kirillov 1
Nikolai Fedorovich Kirillov
, 
Daniil Vladimirovich Baibarodskikh 1
Daniil Vladimirovich Baibarodskikh
, 
Sergey Nikolaevich Shurov 1
Sergey Nikolaevich Shurov
, 
Maksim Victorovich Dmitriev 1
Maksim Victorovich Dmitriev
, 
Dmitriy Pavlovich Zverev 1
Dmitriy Pavlovich Zverev
10.1016/j.mencom.2021.03.035
Published 2021-03-03
Communication , Volume 31, Issue 2, 248-250
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Nikiforova E. A. et al. Reaction of Reformatsky reagents with 2,5-diphenyl-1,3,4-oxadiazole // Mendeleev Communications. 2021. Vol. 31. No. 2. pp. 248-250.
GOST all authors (up to 50) Copy
Nikiforova E. A., Kirillov N. F., Baibarodskikh D. V., Shurov S. N., Dmitriev M. V., Zverev D. P. Reaction of Reformatsky reagents with 2,5-diphenyl-1,3,4-oxadiazole // Mendeleev Communications. 2021. Vol. 31. No. 2. pp. 248-250.
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TY - JOUR
DO - 10.1016/j.mencom.2021.03.035
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.03.035
TI - Reaction of Reformatsky reagents with 2,5-diphenyl-1,3,4-oxadiazole
T2 - Mendeleev Communications
AU - Nikiforova, Elena Aleksandrovna
AU - Kirillov, Nikolai Fedorovich
AU - Baibarodskikh, Daniil Vladimirovich
AU - Shurov, Sergey Nikolaevich
AU - Dmitriev, Maksim Victorovich
AU - Zverev, Dmitriy Pavlovich
PY - 2021
DA - 2021/03/03
PB - Mendeleev Communications
SP - 248-250
IS - 2
VL - 31
ER -
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@article{2021_Nikiforova,
author = {Elena Aleksandrovna Nikiforova and Nikolai Fedorovich Kirillov and Daniil Vladimirovich Baibarodskikh and Sergey Nikolaevich Shurov and Maksim Victorovich Dmitriev and Dmitriy Pavlovich Zverev},
title = {Reaction of Reformatsky reagents with 2,5-diphenyl-1,3,4-oxadiazole},
journal = {Mendeleev Communications},
year = {2021},
volume = {31},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.03.035},
number = {2},
pages = {248--250},
doi = {10.1016/j.mencom.2021.03.035}
}
MLA
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MLA Copy
Nikiforova, Elena Aleksandrovna, et al. “Reaction of Reformatsky reagents with 2,5-diphenyl-1,3,4-oxadiazole.” Mendeleev Communications, vol. 31, no. 2, Mar. 2021, pp. 248-250. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.03.035.

Keywords

1,3,4-oxadiazoles
alicyclic compounds
organozinc compounds
pyrano[2,3-c]pyrazoles
pyrazol-3-ones
Reformatsky reaction
spiro compounds
X-ray analysis

Abstract

The reaction of methyl a-bromoisobutyrate or 1-bromocycloalkanecarboxylates with zinc and 2,5-diphenyl-1,3,4-oxadiazole leads to 5-phenyl-2,4-dihydro-3H-pyrazol-3-one derivatives, with the cycloalkane series affording products of spiro structure. In the case of cyclobutane reactant, 3-phenyl-2,4,5,6-tetrahydropyrano[2,3-c]pyrazole is also formed.

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