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Novel 8-arylidenetetrahydroquinazoline N-oxides: synthesis, photophysical properties and biological evaluation

, 
Dmitry Alekseevich Vasilenko 1
Dmitry Alekseevich Vasilenko
, 
Denis Vadimovich Zverev 1
Denis Vadimovich Zverev
, 
Kirill Sergeyevich Sadovnikov 1
Kirill Sergeyevich Sadovnikov
, 
Yulia Aleksandrovna Gracheva 1
Yulia Aleksandrovna Gracheva
,  , 
Tamara Stepanovna Kuznetsova 1
Tamara Stepanovna Kuznetsova
, 
Elena Rudol'fovna Milaeva 1, 2
Elena Rudol'fovna Milaeva
, 
Elena Borisovna Averina 1, 2
Elena Borisovna Averina
10.1016/j.mencom.2021.01.011
Published 2020-12-30
Communication , Volume 31, Issue 1, 39-41
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Sedenkova K. N. et al. Novel 8-arylidenetetrahydroquinazoline N-oxides: synthesis, photophysical properties and biological evaluation // Mendeleev Communications. 2020. Vol. 31. No. 1. pp. 39-41.
GOST all authors (up to 50) Copy
Sedenkova K. N., Vasilenko D. A., Zverev D. V., Sadovnikov K. S., Gracheva Y. A., Grishin Y. K., Kuznetsova T. S., Milaeva E. R., Averina E. B. Novel 8-arylidenetetrahydroquinazoline N-oxides: synthesis, photophysical properties and biological evaluation // Mendeleev Communications. 2020. Vol. 31. No. 1. pp. 39-41.
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TY - JOUR
DO - 10.1016/j.mencom.2021.01.011
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.01.011
TI - Novel 8-arylidenetetrahydroquinazoline N-oxides: synthesis, photophysical properties and biological evaluation
T2 - Mendeleev Communications
AU - Sedenkova, Kseniya N
AU - Vasilenko, Dmitry Alekseevich
AU - Zverev, Denis Vadimovich
AU - Sadovnikov, Kirill Sergeyevich
AU - Gracheva, Yulia Aleksandrovna
AU - Grishin, Yuri Konstantinovich
AU - Kuznetsova, Tamara Stepanovna
AU - Milaeva, Elena Rudol'fovna
AU - Averina, Elena Borisovna
PY - 2020
DA - 2020/12/30
PB - Mendeleev Communications
SP - 39-41
IS - 1
VL - 31
ER -
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@article{2020_Sedenkova,
author = {Kseniya N Sedenkova and Dmitry Alekseevich Vasilenko and Denis Vadimovich Zverev and Kirill Sergeyevich Sadovnikov and Yulia Aleksandrovna Gracheva and Yuri Konstantinovich Grishin and Tamara Stepanovna Kuznetsova and Elena Rudol'fovna Milaeva and Elena Borisovna Averina},
title = {Novel 8-arylidenetetrahydroquinazoline N-oxides: synthesis, photophysical properties and biological evaluation},
journal = {Mendeleev Communications},
year = {2020},
volume = {31},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.01.011},
number = {1},
pages = {39--41},
doi = {10.1016/j.mencom.2021.01.011}
}
MLA
Cite this
MLA Copy
Sedenkova, Kseniya N., et al. “Novel 8-arylidenetetrahydroquinazoline N-oxides: synthesis, photophysical properties and biological evaluation.” Mendeleev Communications, vol. 31, no. 1, Dec. 2020, pp. 39-41. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2021.01.011.

Keywords

condensation
cyanopyrimidine N-oxides
cytotoxic activity
fluorescent properties
quantum chemical calculations
tetrahydroquinazolines

Abstract

New 8-arylidene-4-cyanotetrahydroquinazoline N-oxides were obtained via the condensation of readily available 4-cyanotetrahydroquinazoline N-oxides with aromatic aldehydes. Some of the synthesized compounds revealed fluorescent properties and moderate cytotoxic activity.

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