Home / Publications / Microflow synthesis of fluorescent markers based on 1,8-naphthalimide for polylactide nanoparticles and bioimaging

Microflow synthesis of fluorescent markers based on 1,8-naphthalimide for polylactide nanoparticles and bioimaging

Maxim Sergeevich Oshchepkov 1
Maxim Sergeevich Oshchepkov
,  , 
Alexey Olegovich Menkov 1
Alexey Olegovich Menkov
, 
Pavel A Melnikov 2
Pavel A Melnikov
,  , 
Inna Nikolaevna Solovieva 1
Inna Nikolaevna Solovieva
, 
Sergey Vital'evich Tkachenko 1
Sergey Vital'evich Tkachenko
, 
Julia A Malinowskaya 2
Julia A Malinowskaya
10.1016/j.mencom.2020.11.019
Published 2020-11-03
Communication , Volume 30, Issue 6, 747-749
5
Share
Cite this
GOST
 | 
Cite this
GOST Copy
Oshchepkov M. S. et al. Microflow synthesis of fluorescent markers based on 1,8-naphthalimide for polylactide nanoparticles and bioimaging // Mendeleev Communications. 2020. Vol. 30. No. 6. pp. 747-749.
GOST all authors (up to 50) Copy
Oshchepkov M. S., Semyonkin A. S., Menkov A. O., Melnikov P. A., Valikhov M. P., Solovieva I. N., Tkachenko S. V., Malinowskaya J. A. Microflow synthesis of fluorescent markers based on 1,8-naphthalimide for polylactide nanoparticles and bioimaging // Mendeleev Communications. 2020. Vol. 30. No. 6. pp. 747-749.
RIS
 | 
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.mencom.2020.11.019
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.11.019
TI - Microflow synthesis of fluorescent markers based on 1,8-naphthalimide for polylactide nanoparticles and bioimaging
T2 - Mendeleev Communications
AU - Oshchepkov, Maxim Sergeevich
AU - Semyonkin, Aleksey Sergeyevich
AU - Menkov, Alexey Olegovich
AU - Melnikov, Pavel A
AU - Valikhov, Marat Petrovich
AU - Solovieva, Inna Nikolaevna
AU - Tkachenko, Sergey Vital'evich
AU - Malinowskaya, Julia A
PY - 2020
DA - 2020/11/03
PB - Mendeleev Communications
SP - 747-749
IS - 6
VL - 30
ER -
BibTex
 | 
Cite this
BibTex (up to 50 authors) Copy
@article{2020_Oshchepkov,
author = {Maxim Sergeevich Oshchepkov and Aleksey Sergeyevich Semyonkin and Alexey Olegovich Menkov and Pavel A Melnikov and Marat Petrovich Valikhov and Inna Nikolaevna Solovieva and Sergey Vital'evich Tkachenko and Julia A Malinowskaya},
title = {Microflow synthesis of fluorescent markers based on 1,8-naphthalimide for polylactide nanoparticles and bioimaging},
journal = {Mendeleev Communications},
year = {2020},
volume = {30},
publisher = {Mendeleev Communications},
month = {Nov},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.11.019},
number = {6},
pages = {747--749},
doi = {10.1016/j.mencom.2020.11.019}
}
MLA
Cite this
MLA Copy
Oshchepkov, Maxim Sergeevich, et al. “Microflow synthesis of fluorescent markers based on 1,8-naphthalimide for polylactide nanoparticles and bioimaging.” Mendeleev Communications, vol. 30, no. 6, Nov. 2020, pp. 747-749. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.11.019.
Views / Downloads
1 / 2

Keywords

1,8-naphthalimide
bioimaging
fluorescent markers
microfluidic synthesis
polylactide

Abstract

Two strategies for the synthesis of the new fluorescent markers based on 1,8-naphthalimide under classical conditions (in a flask) and in a microflow reactor are compared and contrasted. The microflow method provides higher purity of products, better productivity and production time. The resulting markers were used to obtain fluorescently labeled polylactide-based nanoparticles that can be used to study the distribution of polylactide nanoparticles as drug delivery vehicles within tissues and living organisms.

References

1.
Drug Delivery Systems: Past, Present, and Future
Mainardes R., Silva L.
Current Drug Targets, 2004
2.
Recent Advances in Drug Delivery Systems
Martinho N., Damgé C., Reis C.P.
Journal of Biomaterials and Nanobiotechnology, 2011
3.
Polymeric Micelles for Drug Delivery
Croy S., Kwon G.
Current Pharmaceutical Design, 2006
4.
Colloidal drug carriers: achievements and perspectives
Barratt G.
Cellular and Molecular Life Sciences, 2003
5.
How subtle differences in polymer molecular weight affect doxorubicin-loaded PLGA nanoparticles degradation and drug release
Kumskova N., Ermolenko Y., Osipova N., Semyonkin A., Kildeeva N., Gorshkova M., Kovalskii A., Kovshova T., Tarasov V., Kreuter J., Maksimenko O., Gelperina S.
Journal of Microencapsulation, 2020
6.
Toxicological study of doxorubicin‐loaded PLGA nanoparticles for the treatment of glioblastoma
Pereverzeva E., Treschalin I., Treschalin M., Arantseva D., Ermolenko Y., Kumskova N., Maksimenko O., Balabanyan V., Kreuter J., Gelperina S.
International Journal of Pharmaceutics, 2019
7.
Elimination of autofluorescence background from fluorescence tissue images by use of time-gated detection and the AzaDiOxaTriAngulenium (ADOTA) fluorophore
Rich R.M., Stankowska D.L., Maliwal B.P., Sørensen T.J., Laursen B.W., Krishnamoorthy R.R., Gryczynski Z., Borejdo J., Gryczynski I., Fudala R.
Analytical and Bioanalytical Chemistry, 2012
8.
10.1016/j.mencom.2020.11.019_bib0040
Lee
Wiley Interdiscip. Rev.: Nanomed. Nanobiotechnol., 2019
10.
Tiwari G., Tiwari R., Bannerjee S., Bhati L., Pandey S., Pandey P., Sriwastawa B.
International Journal of Pharmaceutical Investigation, 2012
11.
Opportunities and Challenges of Fluorescent Carbon Dots in Translational Optical Imaging
Wang J., Liu G., Leung K., Loffroy R., Lu P., J. Wáng Y.
Current Pharmaceutical Design, 2015
12.
Near infrared labeling of PLGA for in vivo imaging of nanoparticles
Reul R., Tsapis N., Hillaireau H., Sancey L., Mura S., Recher M., Nicolas J., Coll J., Fattal E.
Polymer Chemistry, 2012
13.
Nanoparticles made of fluorescence-labelled Poly(L-lactide-co-glycolide): preparation, stability, and biocompatibility.
Weiss B., Schaefer U.F., Zapp J., Lamprecht A., Stallmach A., Lehr C.
Journal of Nanoscience and Nanotechnology, 2006
14.
A comparative study of non-covalent encapsulation methods for organic dyes into silica nanoparticles
Auger A., Samuel J., Poncelet O., Raccurt O.
Nanoscale Research Letters, 2011
15.
Synthesis and characterization of functionalized magnetic maghemite nanoparticles with fluorescent probe capabilities for biological applications
Perlstein B., Lublin-Tennenbaum T., Marom I., Margel S.
Journal of Biomedical Materials Research - Part B Applied Biomaterials, 2009
16.
Elution of Labile Fluorescent Dye from Nanoparticles during Biological Use
Tenuta T., Monopoli M.P., Kim J., Salvati A., Dawson K.A., Sandin P., Lynch I.
PLoS ONE, 2011
18.
Jarutikorn S., Kraithong S., Sirirak J., Panchan W., Sooksimuang T., Charoenpanich A., Wanichacheva N.
Oriental Journal Of Chemistry, 2019
19.
Synthesis of 4-Nitro-N-phenyl-1,8-naphthalimide Annulated to Thia- and Azacrown Ether Moieties
Fedorova O., Oshchepkov A., Oshchepkov M., Arkhipova A., Panchenko P.
Synthesis, 2017
20.
Naphthalimide-functionalized bisphosphonates for fluorescence detection of calcification in soft tissues
Oshchepkov A., Oshchepkov M., Pavlova G., Ryabova A., Kamagurov S., Tkachenko S., Frolova S., Redchuk A., Popov K., Kataev E.A.
Sensors and Actuators, B: Chemical, 2020
21.
10.1016/j.mencom.2020.11.019_bib0105
Oshchepkov
Int. J. Corros. Scale Inhib., 2019
22.
Conformational Selection in Anion Recognition: cGMP-Selective Binding by a Naphthalimide-Functionalized Amido-Amine Macrocycle
Oshchepkov A.S., Shumilova T.A., Zerson M., Magerle R., Khrustalev V.N., Kataev E.A.
Journal of Organic Chemistry, 2019
24.
Continuous flow microfluidic implementation of a fluorescent marker into a polyacrylate moiety
Oshchepkov M., Solovieva I., Menkov A., Tkachenko S., Udovenko V., Popov K.
Journal of Flow Chemistry, 2020
26.
10.1016/j.mencom.2020.11.019_bib0130
MacDonald
Membrane Trafficking, 2015
27.
10.1016/j.mencom.2020.11.019_bib0135
Rivera
Int. Scholarly Res. Not., 2011
29.
Lysosomal Targeting with Stable and Sensitive Fluorescent Probes (Superior LysoProbes): Applications for Lysosome Labeling and Tracking during Apoptosis
Chen X., Bi Y., Wang T., Li P., Yan X., Hou S., Bammert C.E., Ju J., Gibson K.M., Pavan W.J., Bi L.
Scientific Reports, 2015
30.
Delivery of doxorubicin-loaded PLGA nanoparticles into U87 human glioblastoma cells.
Malinovskaya Y., Melnikov P., Baklaushev V., Gabashvili A., Osipova N., Mantrov S., Ermolenko Y., Maksimenko O., Gorshkova M., Balabanyan V., Kreuter J., Gelperina S.
International Journal of Pharmaceutics, 2017