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Aggregation of water soluble octaanionic phthalocyanines and their photoinactivation antimicrobial effect in vitro

Vladimir V Makarov 1
Vladimir V Makarov
Serafima A Znoyko 1
Serafima A Znoyko
Vladimir E Mayzlish 1
Vladimir E Mayzlish
Andrey Vladimirovich Kustov 1, 2
Andrey Vladimirovich Kustov
Published 2020-08-31
CommunicationVolume 30, Issue 5, 621-623
29
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Berezin D. B. et al. Aggregation of water soluble octaanionic phthalocyanines and their photoinactivation antimicrobial effect in vitro // Mendeleev Communications. 2020. Vol. 30. No. 5. pp. 621-623.
GOST all authors (up to 50) Copy
Berezin D. B., Makarov V. V., Znoyko S. A., Mayzlish V. E., Kustov A. V. Aggregation of water soluble octaanionic phthalocyanines and their photoinactivation antimicrobial effect in vitro // Mendeleev Communications. 2020. Vol. 30. No. 5. pp. 621-623.
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TY - JOUR
DO - 10.1016/j.mencom.2020.09.023
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.09.023
TI - Aggregation of water soluble octaanionic phthalocyanines and their photoinactivation antimicrobial effect in vitro
T2 - Mendeleev Communications
AU - Berezin, Dmitry Borisovich
AU - Makarov, Vladimir V
AU - Znoyko, Serafima A
AU - Mayzlish, Vladimir E
AU - Kustov, Andrey Vladimirovich
PY - 2020
DA - 2020/08/31
PB - Mendeleev Communications
SP - 621-623
IS - 5
VL - 30
ER -
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@article{2020_Berezin,
author = {Dmitry Borisovich Berezin and Vladimir V Makarov and Serafima A Znoyko and Vladimir E Mayzlish and Andrey Vladimirovich Kustov},
title = {Aggregation of water soluble octaanionic phthalocyanines and their photoinactivation antimicrobial effect in vitro},
journal = {Mendeleev Communications},
year = {2020},
volume = {30},
publisher = {Mendeleev Communications},
month = {Aug},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.09.023},
number = {5},
pages = {621--623},
doi = {10.1016/j.mencom.2020.09.023}
}
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Berezin, Dmitry Borisovich, et al. “Aggregation of water soluble octaanionic phthalocyanines and their photoinactivation antimicrobial effect in vitro.” Mendeleev Communications, vol. 30, no. 5, Aug. 2020, pp. 621-623. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.09.023.

Keywords

aggregation
antimicrobial photodynamic therapy
microorganisms photoinactivation
nonionic surfactant
photosensitizer
water soluble phthalocyanine

Abstract

Aggregation of sulfophenylsulfanyl-substituted phthalocyanine and its aluminum complex has been investigated in aqueous solutions of DMF or nonionic surfactant Tween 80 by UV-VIS spectroscopy and DLS. Aluminum complex is less aggregated and 4.5 orders of magnitude stronger bound to the micelles of Tween 80 compared to a metal-free ligand. Under irradiation the phthalocyanine derivatives reveal a pronounced antimicrobial activity towards both Gram(+) and Gram(−) archive microflora in vitro.

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