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An expedient synthesis of 5-alkynyl-6-aryl-2,2′-bipyridines

Maria Igorevna Savchuk 1
Maria Igorevna Savchuk
, 
Alexey P Krinochkin 1, 2
Alexey P Krinochkin
, 
Alluru Rammohan 1
Alluru Rammohan
, 
Albert Faridovich Khasanov 1, 2
Albert Faridovich Khasanov
, 
Dmitrii Sergeevich Kopchuk 1, 2
Dmitrii Sergeevich Kopchuk
, 
Ilya Nikolayevich Egorov 1
Ilya Nikolayevich Egorov
, 
Sougata Santra 1
Sougata Santra
, 
Grigory Vasil'evich Zyryanov 1, 2
Grigory Vasil'evich Zyryanov
, 
Vladimir Leonidovich Rusinov 1, 2
Vladimir Leonidovich Rusinov
, 
Oleg Nikolaevich Chupakhin 1, 2
Oleg Nikolaevich Chupakhin
10.1016/j.mencom.2020.09.019
Published 2020-08-31
Communication , Volume 30, Issue 5, 610-611
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Savchuk M. I. et al. An expedient synthesis of 5-alkynyl-6-aryl-2,2′-bipyridines // Mendeleev Communications. 2020. Vol. 30. No. 5. pp. 610-611.
GOST all authors (up to 50) Copy
Savchuk M. I., Krinochkin A. P., Rammohan A., Khasanov A. F., Kopchuk D. S., Egorov I. N., Santra S., Zyryanov G. V., Rusinov V. L., Chupakhin O. N. An expedient synthesis of 5-alkynyl-6-aryl-2,2′-bipyridines // Mendeleev Communications. 2020. Vol. 30. No. 5. pp. 610-611.
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TY - JOUR
DO - 10.1016/j.mencom.2020.09.019
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.09.019
TI - An expedient synthesis of 5-alkynyl-6-aryl-2,2′-bipyridines
T2 - Mendeleev Communications
AU - Savchuk, Maria Igorevna
AU - Krinochkin, Alexey P
AU - Rammohan, Alluru
AU - Khasanov, Albert Faridovich
AU - Kopchuk, Dmitrii Sergeevich
AU - Egorov, Ilya Nikolayevich
AU - Santra, Sougata
AU - Zyryanov, Grigory Vasil'evich
AU - Rusinov, Vladimir Leonidovich
AU - Chupakhin, Oleg Nikolaevich
PY - 2020
DA - 2020/08/31
PB - Mendeleev Communications
SP - 610-611
IS - 5
VL - 30
ER -
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@article{2020_Savchuk,
author = {Maria Igorevna Savchuk and Alexey P Krinochkin and Alluru Rammohan and Albert Faridovich Khasanov and Dmitrii Sergeevich Kopchuk and Ilya Nikolayevich Egorov and Sougata Santra and Grigory Vasil'evich Zyryanov and Vladimir Leonidovich Rusinov and Oleg Nikolaevich Chupakhin},
title = {An expedient synthesis of 5-alkynyl-6-aryl-2,2′-bipyridines},
journal = {Mendeleev Communications},
year = {2020},
volume = {30},
publisher = {Mendeleev Communications},
month = {Aug},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.09.019},
number = {5},
pages = {610--611},
doi = {10.1016/j.mencom.2020.09.019}
}
MLA
Cite this
MLA Copy
Savchuk, Maria Igorevna, et al. “An expedient synthesis of 5-alkynyl-6-aryl-2,2′-bipyridines.” Mendeleev Communications, vol. 30, no. 5, Aug. 2020, pp. 610-611. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.09.019.

Keywords

1,2,4-triazines
2,2′-bipyridines
acetylenes
aza-Diels–Alder reaction
nucleophilic substitution of hydrogen

Abstract

5-Alkynyl-6-aryl-2,2′-bipyridines were conveniently prepared in two steps comprising oxidative SN H ethynylation of 5-aryl-3-(2-pyridyl)-1,2,4-triazines at position 6. At the second step, the 1,2,4-triazine moiety was transformed into the pyridine one employing aza-Diels–Alder reaction with 2,5-norbornadiene.

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