Home / Publications / Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system

Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system

Ervand G Paronikyan 1
Ervand G Paronikyan
, 
Shushanik Shamir Dashyan 1
Shushanik Shamir Dashyan
, 
Suren Seryozhevich Mamyan 1
Suren Seryozhevich Mamyan
10.1016/j.mencom.2020.03.017
Published 2020-03-02
Communication , Volume 30, Issue 2, 183-184
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Paronikyan E. G., Dashyan S. S., Mamyan S. S. Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system // Mendeleev Communications. 2020. Vol. 30. No. 2. pp. 183-184.
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Paronikyan E. G., Dashyan S. S., Mamyan S. S. Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system // Mendeleev Communications. 2020. Vol. 30. No. 2. pp. 183-184.
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TY - JOUR
DO - 10.1016/j.mencom.2020.03.017
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.03.017
TI - Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system
T2 - Mendeleev Communications
AU - Paronikyan, Ervand G
AU - Dashyan, Shushanik Shamir
AU - Mamyan, Suren Seryozhevich
PY - 2020
DA - 2020/03/02
PB - Mendeleev Communications
SP - 183-184
IS - 2
VL - 30
ER -
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@article{2020_Paronikyan,
author = {Ervand G Paronikyan and Shushanik Shamir Dashyan and Suren Seryozhevich Mamyan},
title = {Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system},
journal = {Mendeleev Communications},
year = {2020},
volume = {30},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.03.017},
number = {2},
pages = {183--184},
doi = {10.1016/j.mencom.2020.03.017}
}
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Paronikyan, Ervand G., et al. “Synthesis of pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines, representatives of a new fused heterocyclic system.” Mendeleev Communications, vol. 30, no. 2, Mar. 2020, pp. 183-184. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.03.017.

Keywords

alkylation
heterocyclization
hydrazines
pyrano[3,4-c]pyridines
pyrano[3,4-c]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyridines
thiones
triazolo[4,3-a]pyridines

Abstract

New effective synthesis of functionalized pyrano[3,4-c]thieno-[3,2-e][1,2,4]triazolo[4,3-a]pyridines comprises nucleophilic substitution in 8-morpholino-6-thioxopyrano[3,4-c]pyridine-5-carbonitrile with hydrazine hydrate followed by sequential heterocyclization with formic acid and chloroacetic acid derivatives.

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