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Synthesis and antiproliferative activity of new chlorin e6 glycoconjugates

Natalia Sergeevna Kuzmina 1
Natalia Sergeevna Kuzmina
Vasilii F Otvagin 1
Vasilii F Otvagin
Lubov Vladimirovna Krylova 1
Lubov Vladimirovna Krylova
Alexander Vladimirovich Nyuchev
Yulia Vital'evna Romanenko 2
Yulia Vital'evna Romanenko
Oscar Iosifovich Koifman 2
Oscar Iosifovich Koifman
Irina V Balalaeva 1
Irina V Balalaeva
Published 2020-03-02
CommunicationVolume 30, Issue 2, 159-161
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Kuzmina N. S. et al. Synthesis and antiproliferative activity of new chlorin e6 glycoconjugates // Mendeleev Communications. 2020. Vol. 30. No. 2. pp. 159-161.
GOST all authors (up to 50) Copy
Kuzmina N. S., Otvagin V. F., Krylova L. V., Nyuchev A. V., Romanenko Y. V., Koifman O. I., Balalaeva I. V., Fedorov A. Y. Synthesis and antiproliferative activity of new chlorin e6 glycoconjugates // Mendeleev Communications. 2020. Vol. 30. No. 2. pp. 159-161.
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TY - JOUR
DO - 10.1016/j.mencom.2020.03.009
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.03.009
TI - Synthesis and antiproliferative activity of new chlorin e6 glycoconjugates
T2 - Mendeleev Communications
AU - Kuzmina, Natalia Sergeevna
AU - Otvagin, Vasilii F
AU - Krylova, Lubov Vladimirovna
AU - Nyuchev, Alexander Vladimirovich
AU - Romanenko, Yulia Vital'evna
AU - Koifman, Oscar Iosifovich
AU - Balalaeva, Irina V
AU - Fedorov, Alexey Yur'evich
PY - 2020
DA - 2020/03/02
PB - Mendeleev Communications
SP - 159-161
IS - 2
VL - 30
ER -
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@article{2020_Kuzmina,
author = {Natalia Sergeevna Kuzmina and Vasilii F Otvagin and Lubov Vladimirovna Krylova and Alexander Vladimirovich Nyuchev and Yulia Vital'evna Romanenko and Oscar Iosifovich Koifman and Irina V Balalaeva and Alexey Yur'evich Fedorov},
title = {Synthesis and antiproliferative activity of new chlorin e6 glycoconjugates},
journal = {Mendeleev Communications},
year = {2020},
volume = {30},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.03.009},
number = {2},
pages = {159--161},
doi = {10.1016/j.mencom.2020.03.009}
}
MLA
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Kuzmina, Natalia Sergeevna, et al. “Synthesis and antiproliferative activity of new chlorin e6 glycoconjugates.” Mendeleev Communications, vol. 30, no. 2, Mar. 2020, pp. 159-161. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.03.009.

Keywords

A431 cells
chlorin e6
glycoconjugate
photodynamic therapy
water soluble

Abstract

New water soluble conjugates of chlorin e6 derivative–zinc complex with β-d-galactose or β-d-glucose have been synthesized as potential agents for the photodynamic therapy of cancer. They exhibit photoinduced cytotoxicity at low micromolar concentrations with IC50(dark)/IC50(light) ratio of ∼50.

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