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Synthesis and antitumor activity of methanofullerenes equipped with norbornadiene and quadricyclane moieties

, 
Arslan Rifkhatovich Akhmetov 1
Arslan Rifkhatovich Akhmetov
, 
Vladimir Anatol'evich D'yakonov 1
Vladimir Anatol'evich D'yakonov
, 
Lilya Useinovna Dzhemileva 1
Lilya Useinovna Dzhemileva
, 
Milyausha Musimovna Yunusbaeva 1
Milyausha Musimovna Yunusbaeva
, 
Airat Ramilevich Tuktarov 1
Airat Ramilevich Tuktarov
10.1016/j.mencom.2020.03.006
Published 2020-03-02
Communication , Volume 30, Issue 2, 150-152
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Dzhemilev U. M. et al. Synthesis and antitumor activity of methanofullerenes equipped with norbornadiene and quadricyclane moieties // Mendeleev Communications. 2020. Vol. 30. No. 2. pp. 150-152.
GOST all authors (up to 50) Copy
Dzhemilev U. M., Akhmetov A. R., D'yakonov V. A., Dzhemileva L. U., Yunusbaeva M. M., Tuktarov A. R. Synthesis and antitumor activity of methanofullerenes equipped with norbornadiene and quadricyclane moieties // Mendeleev Communications. 2020. Vol. 30. No. 2. pp. 150-152.
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TY - JOUR
DO - 10.1016/j.mencom.2020.03.006
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.03.006
TI - Synthesis and antitumor activity of methanofullerenes equipped with norbornadiene and quadricyclane moieties
T2 - Mendeleev Communications
AU - Dzhemilev, Usein Memetovich
AU - Akhmetov, Arslan Rifkhatovich
AU - D'yakonov, Vladimir Anatol'evich
AU - Dzhemileva, Lilya Useinovna
AU - Yunusbaeva, Milyausha Musimovna
AU - Tuktarov, Airat Ramilevich
PY - 2020
DA - 2020/03/02
PB - Mendeleev Communications
SP - 150-152
IS - 2
VL - 30
ER -
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@article{2020_Dzhemilev,
author = {Usein Memetovich Dzhemilev and Arslan Rifkhatovich Akhmetov and Vladimir Anatol'evich D'yakonov and Lilya Useinovna Dzhemileva and Milyausha Musimovna Yunusbaeva and Airat Ramilevich Tuktarov},
title = {Synthesis and antitumor activity of methanofullerenes equipped with norbornadiene and quadricyclane moieties},
journal = {Mendeleev Communications},
year = {2020},
volume = {30},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.03.006},
number = {2},
pages = {150--152},
doi = {10.1016/j.mencom.2020.03.006}
}
MLA
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Dzhemilev, Usein Memetovich, et al. “Synthesis and antitumor activity of methanofullerenes equipped with norbornadiene and quadricyclane moieties.” Mendeleev Communications, vol. 30, no. 2, Mar. 2020, pp. 150-152. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2020.03.006.

Keywords

C60 fullerene
cytotoxic activity
methanofullerenes
norbornadiene
quadricyclane

Abstract

Hybrids composed of 3-pentylnorbornadiene-2-carboxylic acid or its quadricyclane isomer molecules linked to methano-C60 fullerene via triethylene glycol spacer were synthesized by the Bingel–Hirsch reaction. The quadricyclane derivative possesses markedly higher apoptosis-inducing activity against the Jurkat tumor cells than the norbornadiene one.

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