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Versatile approach to naphthoquinone phosphonium salts and evaluation of their biological activity

Nadezhda R Khasiyatullina 1
Nadezhda R Khasiyatullina
,  , 
Sumbel K Gumerova 1
Sumbel K Gumerova
, 
Alexandra Dmitrievna Voloshina 1
Alexandra Dmitrievna Voloshina
, 
Anastasia Sergeevna Sapunova 1
Anastasia Sergeevna Sapunova
10.1016/j.mencom.2019.07.027
Published 2019-07-01
Communication , Volume 29, Issue 4, 435-437
16
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Khasiyatullina N. R. et al. Versatile approach to naphthoquinone phosphonium salts and evaluation of their biological activity // Mendeleev Communications. 2019. Vol. 29. No. 4. pp. 435-437.
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Khasiyatullina N. R., Mironov V. F., Gumerova S. K., Voloshina A. D., Sapunova A. S. Versatile approach to naphthoquinone phosphonium salts and evaluation of their biological activity // Mendeleev Communications. 2019. Vol. 29. No. 4. pp. 435-437.
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TY - JOUR
DO - 10.1016/j.mencom.2019.07.027
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.07.027
TI - Versatile approach to naphthoquinone phosphonium salts and evaluation of their biological activity
T2 - Mendeleev Communications
AU - Khasiyatullina, Nadezhda R
AU - Mironov, Vladimir Fedorovich
AU - Gumerova, Sumbel K
AU - Voloshina, Alexandra Dmitrievna
AU - Sapunova, Anastasia Sergeevna
PY - 2019
DA - 2019/07/01
PB - Mendeleev Communications
SP - 435-437
IS - 4
VL - 29
ER -
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@article{2019_Khasiyatullina,
author = {Nadezhda R Khasiyatullina and Vladimir Fedorovich Mironov and Sumbel K Gumerova and Alexandra Dmitrievna Voloshina and Anastasia Sergeevna Sapunova},
title = {Versatile approach to naphthoquinone phosphonium salts and evaluation of their biological activity},
journal = {Mendeleev Communications},
year = {2019},
volume = {29},
publisher = {Mendeleev Communications},
month = {Jul},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.07.027},
number = {4},
pages = {435--437},
doi = {10.1016/j.mencom.2019.07.027}
}
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Khasiyatullina, Nadezhda R., et al. “Versatile approach to naphthoquinone phosphonium salts and evaluation of their biological activity.” Mendeleev Communications, vol. 29, no. 4, Jul. 2019, pp. 435-437. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.07.027.

Abstract

A new efficient method for the synthesis of 1,4-dihydroxy-2-naphthylmethyl-and 1,4-dioxo-2(1H,4H)-2-naphthylmethyl-phosphonium salts by reactions of 2-methyl-1,4-naphtho-quinone with appropriate P–H-phosphonium trifluoroacetates has been suggested. The reactions were carried out under mild conditions and provided high yields of target compounds. Representative reaction products have been found to possess moderate antimicrobial and antitumor activity.

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