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6-Amino-5-hydroxy-2,3-dimethylpyrimidin-4(3H)-one as an efficient inhibitor of free radical oxidation

Stanislav Anatol'evich Grabovskiy 1
Stanislav Anatol'evich Grabovskiy
, 
Yulia S Grabovskaya 1
Yulia S Grabovskaya
, 
Arcadiy Vyacheslavovich Antipin 1
Arcadiy Vyacheslavovich Antipin
, 
Natalia Nurullovna Kabal'nova 1
Natalia Nurullovna Kabal'nova
10.1016/j.mencom.2019.07.019
Published 2019-07-01
Communication , Volume 29, Issue 4, 414-416
4
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Grabovskiy S. A. et al. 6-Amino-5-hydroxy-2,3-dimethylpyrimidin-4(3H)-one as an efficient inhibitor of free radical oxidation // Mendeleev Communications. 2019. Vol. 29. No. 4. pp. 414-416.
GOST all authors (up to 50) Copy
Grabovskiy S. A., Grabovskaya Y. S., Antipin A. V., Kabal'nova N. N. 6-Amino-5-hydroxy-2,3-dimethylpyrimidin-4(3H)-one as an efficient inhibitor of free radical oxidation // Mendeleev Communications. 2019. Vol. 29. No. 4. pp. 414-416.
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TY - JOUR
DO - 10.1016/j.mencom.2019.07.019
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.07.019
TI - 6-Amino-5-hydroxy-2,3-dimethylpyrimidin-4(3H)-one as an efficient inhibitor of free radical oxidation
T2 - Mendeleev Communications
AU - Grabovskiy, Stanislav Anatol'evich
AU - Grabovskaya, Yulia S
AU - Antipin, Arcadiy Vyacheslavovich
AU - Kabal'nova, Natalia Nurullovna
PY - 2019
DA - 2019/07/01
PB - Mendeleev Communications
SP - 414-416
IS - 4
VL - 29
ER -
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@article{2019_Grabovskiy,
author = {Stanislav Anatol'evich Grabovskiy and Yulia S Grabovskaya and Arcadiy Vyacheslavovich Antipin and Natalia Nurullovna Kabal'nova},
title = {6-Amino-5-hydroxy-2,3-dimethylpyrimidin-4(3H)-one as an efficient inhibitor of free radical oxidation},
journal = {Mendeleev Communications},
year = {2019},
volume = {29},
publisher = {Mendeleev Communications},
month = {Jul},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.07.019},
number = {4},
pages = {414--416},
doi = {10.1016/j.mencom.2019.07.019}
}
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Grabovskiy, Stanislav Anatol'evich, et al. “6-Amino-5-hydroxy-2,3-dimethylpyrimidin-4(3H)-one as an efficient inhibitor of free radical oxidation.” Mendeleev Communications, vol. 29, no. 4, Jul. 2019, pp. 414-416. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.07.019.

Abstract

6-Amino-5-hydroxy-2,3-dimethylpyrimidin-4(3H)-one inhibits initiated styrene oxidation with the same efficiency as vitamin E compounds. Calculations at M05/MG3S level of theory for the abstraction of a hydrogen atom by a peroxyl radical indicate an early transition state, which closely resembles a pre-reaction hydrogen bond-containing complex responsible for the high rate constant.

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