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Reaction of methyl bromocycloalkanecarboxylates with zinc and dihydroisoquinoline derivative

Elena Aleksandrovna Nikiforova 1
Elena Aleksandrovna Nikiforova
, 
Nikolai Fedorovich Kirillov 1
Nikolai Fedorovich Kirillov
, 
Vladislav Sergeevich Melekhin 1
Vladislav Sergeevich Melekhin
, 
Pavel Alexandrovich Slepukhin 2
Pavel Alexandrovich Slepukhin
10.1016/j.mencom.2019.07.011
Published 2019-07-01
Communication , Volume 29, Issue 4, 393-394
3
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Nikiforova E. A. et al. Reaction of methyl bromocycloalkanecarboxylates with zinc and dihydroisoquinoline derivative // Mendeleev Communications. 2019. Vol. 29. No. 4. pp. 393-394.
GOST all authors (up to 50) Copy
Nikiforova E. A., Kirillov N. F., Melekhin V. S., Slepukhin P. A. Reaction of methyl bromocycloalkanecarboxylates with zinc and dihydroisoquinoline derivative // Mendeleev Communications. 2019. Vol. 29. No. 4. pp. 393-394.
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TY - JOUR
DO - 10.1016/j.mencom.2019.07.011
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.07.011
TI - Reaction of methyl bromocycloalkanecarboxylates with zinc and dihydroisoquinoline derivative
T2 - Mendeleev Communications
AU - Nikiforova, Elena Aleksandrovna
AU - Kirillov, Nikolai Fedorovich
AU - Melekhin, Vladislav Sergeevich
AU - Slepukhin, Pavel Alexandrovich
PY - 2019
DA - 2019/07/01
PB - Mendeleev Communications
SP - 393-394
IS - 4
VL - 29
ER -
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@article{2019_Nikiforova,
author = {Elena Aleksandrovna Nikiforova and Nikolai Fedorovich Kirillov and Vladislav Sergeevich Melekhin and Pavel Alexandrovich Slepukhin},
title = {Reaction of methyl bromocycloalkanecarboxylates with zinc and dihydroisoquinoline derivative},
journal = {Mendeleev Communications},
year = {2019},
volume = {29},
publisher = {Mendeleev Communications},
month = {Jul},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.07.011},
number = {4},
pages = {393--394},
doi = {10.1016/j.mencom.2019.07.011}
}
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MLA Copy
Nikiforova, Elena Aleksandrovna, et al. “Reaction of methyl bromocycloalkanecarboxylates with zinc and dihydroisoquinoline derivative.” Mendeleev Communications, vol. 29, no. 4, Jul. 2019, pp. 393-394. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.07.011.

Abstract

The reaction of 5–7-membered methyl 1-bromocycloalkanecarboxylates with zinc and 6,7-dimethoxy-3,4-dihydroisoquinoline leads to 7,8-dimethoxy-5,9b-dihydro-2H,4H-spiro{azeto[2,1-a]isoquinoline-1,1′-cycloalkan}-2-ones. In the case of 1-bromocyclobutanecarboxylate, 9′,10′-dimethoxy-7′,11b′-dihydro-2′H,4′H,6′H-dispiro{cyclobutane-1,1′-pyrido[2,1-a]isoquinoline-3′,1″-cyclobutane}-2′,4′-dione is formed. The structures of the products were confirmed by X-ray diffraction.

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