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Synthesis and cytotoxicity of novel γ-piperidone-containing dibenzo-1,7-diaza-14-crown-4 ethers

Anh Tuan Le 1
Anh Tuan Le
, 
Van T.T. Tran 1
Van T.T. Tran
, 
Hieu Hong Truong 2
Hieu Hong Truong
, 
Linh M Nguyen 1, 3
Linh M Nguyen
, 
Duc M Luong 1
Duc M Luong
, 
Thuyen T Do 1
Thuyen T Do
, 
Dat T Nguyen 1
Dat T Nguyen
, 
Nhung Thi Dao 1
Nhung Thi Dao
, 
Dat T Le 1
Dat T Le
, 
Anatoly Timofeevich Soldatenkov 2
Anatoly Timofeevich Soldatenkov
, 
Victor Nikolaevich Khrustalev 2, 4
Victor Nikolaevich Khrustalev
10.1016/j.mencom.2019.07.004
Published 2019-07-01
Communication , Volume 29, Issue 4, 375-377
14
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Le A. T. et al. Synthesis and cytotoxicity of novel γ-piperidone-containing dibenzo-1,7-diaza-14-crown-4 ethers // Mendeleev Communications. 2019. Vol. 29. No. 4. pp. 375-377.
GOST all authors (up to 50) Copy
Le A. T., Tran V. T., Truong H. H., Nguyen L. M., Luong D. M., Do T. T., Nguyen D. T., Dao N. T., Le D. T., Soldatenkov A. T., Khrustalev V. N. Synthesis and cytotoxicity of novel γ-piperidone-containing dibenzo-1,7-diaza-14-crown-4 ethers // Mendeleev Communications. 2019. Vol. 29. No. 4. pp. 375-377.
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TY - JOUR
DO - 10.1016/j.mencom.2019.07.004
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.07.004
TI - Synthesis and cytotoxicity of novel γ-piperidone-containing dibenzo-1,7-diaza-14-crown-4 ethers
T2 - Mendeleev Communications
AU - Le, Anh Tuan
AU - Tran, Van T.T.
AU - Truong, Hieu Hong
AU - Nguyen, Linh M
AU - Luong, Duc M
AU - Do, Thuyen T
AU - Nguyen, Dat T
AU - Dao, Nhung Thi
AU - Le, Dat T
AU - Soldatenkov, Anatoly Timofeevich
AU - Khrustalev, Victor Nikolaevich
PY - 2019
DA - 2019/07/01
PB - Mendeleev Communications
SP - 375-377
IS - 4
VL - 29
ER -
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@article{2019_Le,
author = {Anh Tuan Le and Van T.T. Tran and Hieu Hong Truong and Linh M Nguyen and Duc M Luong and Thuyen T Do and Dat T Nguyen and Nhung Thi Dao and Dat T Le and Anatoly Timofeevich Soldatenkov and Victor Nikolaevich Khrustalev},
title = {Synthesis and cytotoxicity of novel γ-piperidone-containing dibenzo-1,7-diaza-14-crown-4 ethers},
journal = {Mendeleev Communications},
year = {2019},
volume = {29},
publisher = {Mendeleev Communications},
month = {Jul},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.07.004},
number = {4},
pages = {375--377},
doi = {10.1016/j.mencom.2019.07.004}
}
MLA
Cite this
MLA Copy
Le, Anh Tuan, et al. “Synthesis and cytotoxicity of novel γ-piperidone-containing dibenzo-1,7-diaza-14-crown-4 ethers.” Mendeleev Communications, vol. 29, no. 4, Jul. 2019, pp. 375-377. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.07.004.

Abstract

For the development of new antitumor agents, novel dibenzo-1,7-diaza-14-crown-4 ethers containing γ-piperidone moiety were synthesized by a domino condensation of new podands, ketones and ammonium acetate. The crystal structure of one Ts of them was studied by X-ray diffraction. Four crown compounds were evaluated in vitro for cytotoxic activity against 5 human cancer cell lines.

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