Abstract
The variation of synthesis temperature made it possible to produce artificial ferritins possessing different structural and magnetic properties, size distribution, and colloidal stability. The effect of synthesis temperature on the core structure and stability of protein shell was investigated using small-angle neutron scattering, small-angle X-ray scattering, SQUID magnetometry, dynamic light scattering, and zeta potential measurements. The optimal temperature was established for the synthesis of artificial ferritin suitable for biomedical imaging applications at ∼60°C, which is close to the protein denaturation temperature.
References
1.
Jutz G., van Rijn P., Santos Miranda B., Böker A.
Chemical Reviews,
2015
2.
Meldrum F.C., Douglas T., Levi S., Arosio P., Mann S.
Journal of Inorganic Biochemistry,
1995
3.
Douglas T., Stark V.T.
Inorganic Chemistry,
2000
4.
Meldrum F.C., Heywood B.R., Mann S.
Science,
1992
5.
Theil E.C., Behera R.K., Tosha T.
Coordination Chemistry Reviews,
2013
6.
Stefanini S., Cavallo S., Wang C., Tataseo P., Vecchini P., Giartosio A., Chiancone E.
Archives of Biochemistry and Biophysics,
1996
7.
Wong K.K., Douglas T., Gider S., Awschalom D.D., Mann S.
Chemistry of Materials,
1998
8.
Martínez-Pérez M.J., de Miguel R., Carbonera C., Martínez-Júlvez M., Lostao A., Piquer C., Gómez-Moreno C., Bartolomé J., Luis F.
Nanotechnology,
2010
9.
Melníková L., Petrenko V.I., Avdeev M.V., Garamus V.M., Almásy L., Ivankov O.I., Bulavin L.A., Mitróová Z., Kopčanský P.
Colloids and Surfaces B: Biointerfaces,
2014
10.
Melnikova L., Petrenko V.I., Avdeev M.V., Ivankov O.I., Bulavin L.A., Garamus V.M., Almásy L., Mitroova Z., Kopcansky P.
Journal of Magnetism and Magnetic Materials,
2015
11.
Melníková L., Mitróová Z., Timko M., Kováč J., Avdeev M.V., Petrenko V.I., Garamus V.M., Almásy L., Kopčanský P.
Mendeleev Communications,
2014
12.
Balejčíková L., Garamus V.M., Avdeev M.V., Petrenko V.I., Almásy L., Kopčanský P.
Colloids and Surfaces B: Biointerfaces,
2017
13.
Cowley J.M., Janney D.E., Gerkin R.C., Buseck P.R.
Journal of Structural Biology,
2000
14.
10.1016/j.mencom.2019.05.012_bib0070
Testa
Proteins of Iron Metabolism,
2001
15.
10.1016/j.mencom.2019.05.012_bib0075
Koorts
Acute Phase Proteins: Regulation and Functions of Acute Phase Proteins,
2011
16.
Smith M.A., Harris P.L., Sayre L.M., Perry G.
Proceedings of the National Academy of Sciences of the United States of America,
1997
17.
Dobson J.
FEBS Letters,
2001
18.
BULTE J.W., DOUGLAS T., MANN S., FRANKEL R.B., MOSKOWITZ B.M., BROOKS R.A., BAUMGARNER C.D., VYMAZAL J., FRANK J.A.
Investigative Radiology,
2006
19.
Bulte J.W., Douglas T., Mann S., Frankel R.B., Moskowitz B.M., Brooks R.A., Baumgarner C.D., Vymazal J., Strub M., Frank J.A.
Journal of Magnetic Resonance Imaging,
1994
20.
Clavijo Jordan V., Caplan M.R., Bennett K.M.
Magnetic Resonance in Medicine,
2010
21.
Zhao Y., Liang M., Li X., Fan K., Xiao J., Li Y., Shi H., Wang F., Choi H.S., Cheng D., Yan X.
ACS Nano,
2016
22.
Strbak O., Balejcikova L., Baciak L., Kovac J., Masarova-Kozelova M., Krafcik A., Dobrota D., Kopcansky P.
Journal Physics D: Applied Physics,
2017