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Preparation of the diastereomerically pure 2S-hydroxy derivative of dihydrolevoglucosenone (cyrene)

Bulat Tagirovich Sharipov 1
Bulat Tagirovich Sharipov
Anna Nikolaevna Davydova 1
Anna Nikolaevna Davydova
Liliya Khalitovna Faizullina 1
Liliya Khalitovna Faizullina
Farid Abdullovich Valeev 1
Farid Abdullovich Valeev
Published 2019-03-01
CommunicationVolume 29, Issue 2, 200-202
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Sharipov B. T. et al. Preparation of the diastereomerically pure 2S-hydroxy derivative of dihydrolevoglucosenone (cyrene) // Mendeleev Communications. 2019. Vol. 29. No. 2. pp. 200-202.
GOST all authors (up to 50) Copy
Sharipov B. T., Davydova A. N., Faizullina L. K., Valeev F. A. Preparation of the diastereomerically pure 2S-hydroxy derivative of dihydrolevoglucosenone (cyrene) // Mendeleev Communications. 2019. Vol. 29. No. 2. pp. 200-202.
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TY - JOUR
DO - 10.1016/j.mencom.2019.03.029
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.03.029
TI - Preparation of the diastereomerically pure 2S-hydroxy derivative of dihydrolevoglucosenone (cyrene)
T2 - Mendeleev Communications
AU - Sharipov, Bulat Tagirovich
AU - Davydova, Anna Nikolaevna
AU - Faizullina, Liliya Khalitovna
AU - Valeev, Farid Abdullovich
PY - 2019
DA - 2019/03/01
PB - Mendeleev Communications
SP - 200-202
IS - 2
VL - 29
ER -
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@article{2019_Sharipov,
author = {Bulat Tagirovich Sharipov and Anna Nikolaevna Davydova and Liliya Khalitovna Faizullina and Farid Abdullovich Valeev},
title = {Preparation of the diastereomerically pure 2S-hydroxy derivative of dihydrolevoglucosenone (cyrene)},
journal = {Mendeleev Communications},
year = {2019},
volume = {29},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.03.029},
number = {2},
pages = {200--202},
doi = {10.1016/j.mencom.2019.03.029}
}
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Sharipov, Bulat Tagirovich, et al. “Preparation of the diastereomerically pure 2S-hydroxy derivative of dihydrolevoglucosenone (cyrene).” Mendeleev Communications, vol. 29, no. 2, Mar. 2019, pp. 200-202. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.03.029.

Abstract

Diastereomerically pure levoglucosenone alcohol, synthesized from levoglucosenone, upon hydrogenation on Raney Ni or Pd/BaSO4 undergoes epimerization at C2 atom caused by formation of cyrene by-product and its subsequent non-specific reduction. A microbiological stereospecific technique using baker's yeast (Saccharomyces cerevisiae) has been developed levoglucosenone for cyrene reduction into cyrene alcohol and also applied to reduce 4-alkoxy and 4-benzyloxy derivatives of cyrene.

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