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2,3,5-Trichlorocyclopent-2-enone derivatives in the Friedel–Crafts reaction with methoxybenzenes and the anticancer activity of the products

Victor Anatol'evich Egorov 1
Victor Anatol'evich Egorov
, 
Fanuza Arslanovna Gimalova 1
Fanuza Arslanovna Gimalova
, 
Zulfiya Rustamovna Zileeva 2
Zulfiya Rustamovna Zileeva
, 
Liana Fanzilevna Zainullina 2
Liana Fanzilevna Zainullina
, 
Yulia Venerovna Vakhitova 2
Yulia Venerovna Vakhitova
, 
Mansur Sagar'yarovich Miftakhov 1
Mansur Sagar'yarovich Miftakhov
10.1016/j.mencom.2019.03.019
Published 2019-03-01
Communication , Volume 29, Issue 2, 174-175
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Egorov V. A. et al. 2,3,5-Trichlorocyclopent-2-enone derivatives in the Friedel–Crafts reaction with methoxybenzenes and the anticancer activity of the products // Mendeleev Communications. 2019. Vol. 29. No. 2. pp. 174-175.
GOST all authors (up to 50) Copy
Egorov V. A., Gimalova F. A., Zileeva Z. R., Zainullina L. F., Vakhitova Y. V., Miftakhov M. S. 2,3,5-Trichlorocyclopent-2-enone derivatives in the Friedel–Crafts reaction with methoxybenzenes and the anticancer activity of the products // Mendeleev Communications. 2019. Vol. 29. No. 2. pp. 174-175.
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TY - JOUR
DO - 10.1016/j.mencom.2019.03.019
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.03.019
TI - 2,3,5-Trichlorocyclopent-2-enone derivatives in the Friedel–Crafts reaction with methoxybenzenes and the anticancer activity of the products
T2 - Mendeleev Communications
AU - Egorov, Victor Anatol'evich
AU - Gimalova, Fanuza Arslanovna
AU - Zileeva, Zulfiya Rustamovna
AU - Zainullina, Liana Fanzilevna
AU - Vakhitova, Yulia Venerovna
AU - Miftakhov, Mansur Sagar'yarovich
PY - 2019
DA - 2019/03/01
PB - Mendeleev Communications
SP - 174-175
IS - 2
VL - 29
ER -
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@article{2019_Egorov,
author = {Victor Anatol'evich Egorov and Fanuza Arslanovna Gimalova and Zulfiya Rustamovna Zileeva and Liana Fanzilevna Zainullina and Yulia Venerovna Vakhitova and Mansur Sagar'yarovich Miftakhov},
title = {2,3,5-Trichlorocyclopent-2-enone derivatives in the Friedel–Crafts reaction with methoxybenzenes and the anticancer activity of the products},
journal = {Mendeleev Communications},
year = {2019},
volume = {29},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.03.019},
number = {2},
pages = {174--175},
doi = {10.1016/j.mencom.2019.03.019}
}
MLA
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Egorov, Victor Anatol'evich, et al. “2,3,5-Trichlorocyclopent-2-enone derivatives in the Friedel–Crafts reaction with methoxybenzenes and the anticancer activity of the products.” Mendeleev Communications, vol. 29, no. 2, Mar. 2019, pp. 174-175. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.03.019.

Abstract

The Friedel–Crafts-type reaction of 5-allyl-2,3,5-trichlorocyclopent-2-enones with mono-, di- and trimethoxybenzenes affords the arene ketovinylation products with the cleavage of C3–Cl bond in the starting trichlorocyclopentenones. The cytotoxocity of the products toward normal HEK293 cell lines and three cancer cell lines, SH-SY5Y, A549 and MCF-7, was evaluated.

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