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The first synthesis of 7-prenylisatin

Dawei Liang 1
Dawei Liang
, 
Yueqiu Wang 1
Yueqiu Wang
1 Department of Pharmacy & Medical Laboratory, Ya'an Vocational College, Ya'an, China
10.1016/j.mencom.2019.03.018
Published 2019-03-01
Communication , Volume 29, Issue 2, 172-173
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Liang D., Wang Y. The first synthesis of 7-prenylisatin // Mendeleev Communications. 2019. Vol. 29. No. 2. pp. 172-173.
GOST all authors (up to 50) Copy
Liang D., Wang Y. The first synthesis of 7-prenylisatin // Mendeleev Communications. 2019. Vol. 29. No. 2. pp. 172-173.
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TY - JOUR
DO - 10.1016/j.mencom.2019.03.018
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.03.018
TI - The first synthesis of 7-prenylisatin
T2 - Mendeleev Communications
AU - Liang, Dawei
AU - Wang, Yueqiu
PY - 2019
DA - 2019/03/01
PB - Mendeleev Communications
SP - 172-173
IS - 2
VL - 29
ER -
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@article{2019_Liang,
author = {Dawei Liang and Yueqiu Wang},
title = {The first synthesis of 7-prenylisatin},
journal = {Mendeleev Communications},
year = {2019},
volume = {29},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.03.018},
number = {2},
pages = {172--173},
doi = {10.1016/j.mencom.2019.03.018}
}
MLA
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MLA Copy
Liang, Dawei, and Yueqiu Wang. “The first synthesis of 7-prenylisatin.” Mendeleev Communications, vol. 29, no. 2, Mar. 2019, pp. 172-173. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.03.018.

Abstract

The first synthesis of 7-prenylisatin, an isatin-type antibiotic with prominent activity against Bacillus subtilis, has been accomplished in 16% overall yield from 2-methylbut-3-en-2-ol and aniline via a five-step procedure. The protocol includes the aromatic aza-Claisen rearrangement and the Sandmeyer isonitrosoacetanilide isatin synthesis as key steps.

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