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The novel structural modification of pyridoxal via its cyclization into 2-acyl- and 2-heteroarylfuro[2,3-c]pyridines

Anatolii Savel'evich Morkovnik 1
Anatolii Savel'evich Morkovnik
, 
Alexander Aleksandrovich Zubenko 2
Alexander Aleksandrovich Zubenko
, 
Lyudmila Nikolaevna Divaeva 1
Lyudmila Nikolaevna Divaeva
, 
Victor Georgievich Kartsev 3
Victor Georgievich Kartsev
, 
Gennadii Sergeevich Borodkin 1
Gennadii Sergeevich Borodkin
, 
Alexander Ivanovich Klimenko 4
Alexander Ivanovich Klimenko
2 North-Caucasian Zonal Research Veterinary Institute, Novocherkassk, Russian Federation
3 'InterBioScreen Ltd.', Chernogolovka, Moscow Region, Russian Federation
10.1016/j.mencom.2019.01.040
Published 2018-12-28
Communication , Volume 29, Issue 1, 116-118
2
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Morkovnik A. S. et al. The novel structural modification of pyridoxal via its cyclization into 2-acyl- and 2-heteroarylfuro[2,3-c]pyridines // Mendeleev Communications. 2018. Vol. 29. No. 1. pp. 116-118.
GOST all authors (up to 50) Copy
Morkovnik A. S., Zubenko A. A., Divaeva L. N., Kartsev V. G., Borodkin G. S., Klimenko A. I. The novel structural modification of pyridoxal via its cyclization into 2-acyl- and 2-heteroarylfuro[2,3-c]pyridines // Mendeleev Communications. 2018. Vol. 29. No. 1. pp. 116-118.
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TY - JOUR
DO - 10.1016/j.mencom.2019.01.040
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.01.040
TI - The novel structural modification of pyridoxal via its cyclization into 2-acyl- and 2-heteroarylfuro[2,3-c]pyridines
T2 - Mendeleev Communications
AU - Morkovnik, Anatolii Savel'evich
AU - Zubenko, Alexander Aleksandrovich
AU - Divaeva, Lyudmila Nikolaevna
AU - Kartsev, Victor Georgievich
AU - Borodkin, Gennadii Sergeevich
AU - Klimenko, Alexander Ivanovich
PY - 2018
DA - 2018/12/28
PB - Mendeleev Communications
SP - 116-118
IS - 1
VL - 29
ER -
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@article{2018_Morkovnik,
author = {Anatolii Savel'evich Morkovnik and Alexander Aleksandrovich Zubenko and Lyudmila Nikolaevna Divaeva and Victor Georgievich Kartsev and Gennadii Sergeevich Borodkin and Alexander Ivanovich Klimenko},
title = {The novel structural modification of pyridoxal via its cyclization into 2-acyl- and 2-heteroarylfuro[2,3-c]pyridines},
journal = {Mendeleev Communications},
year = {2018},
volume = {29},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.01.040},
number = {1},
pages = {116--118},
doi = {10.1016/j.mencom.2019.01.040}
}
MLA
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MLA Copy
Morkovnik, Anatolii Savel'evich, et al. “The novel structural modification of pyridoxal via its cyclization into 2-acyl- and 2-heteroarylfuro[2,3-c]pyridines.” Mendeleev Communications, vol. 29, no. 1, Dec. 2018, pp. 116-118. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.01.040.

Abstract

A simple method for pyridoxal structural modification via furan ring closure was developed resulting in 2-acyl- and 2-heteroarylfuro[2,3-c]pyridines. The reaction products can be proposed as pyridoxal mimetics to inhibit pyridoxal 5′-phosphate-dependent enzymes.

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