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Reactions of chromone-3-carboxamides with 2-cyanothioacetamides

Mikhail Yur'evich Kornev 1
Mikhail Yur'evich Kornev
, 
Denis Sergeevich Tishin 1
Denis Sergeevich Tishin
, 
Vyacheslav Yakovlevich Sosnovskikh 1
Vyacheslav Yakovlevich Sosnovskikh
10.1016/j.mencom.2019.01.022
Published 2018-12-28
Communication , Volume 29, Issue 1, 67-68
6
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Kornev M. Y., Tishin D. S., Sosnovskikh V. Y. Reactions of chromone-3-carboxamides with 2-cyanothioacetamides // Mendeleev Communications. 2018. Vol. 29. No. 1. pp. 67-68.
GOST all authors (up to 50) Copy
Kornev M. Y., Tishin D. S., Sosnovskikh V. Y. Reactions of chromone-3-carboxamides with 2-cyanothioacetamides // Mendeleev Communications. 2018. Vol. 29. No. 1. pp. 67-68.
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TY - JOUR
DO - 10.1016/j.mencom.2019.01.022
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.01.022
TI - Reactions of chromone-3-carboxamides with 2-cyanothioacetamides
T2 - Mendeleev Communications
AU - Kornev, Mikhail Yur'evich
AU - Tishin, Denis Sergeevich
AU - Sosnovskikh, Vyacheslav Yakovlevich
PY - 2018
DA - 2018/12/28
PB - Mendeleev Communications
SP - 67-68
IS - 1
VL - 29
ER -
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@article{2018_Kornev,
author = {Mikhail Yur'evich Kornev and Denis Sergeevich Tishin and Vyacheslav Yakovlevich Sosnovskikh},
title = {Reactions of chromone-3-carboxamides with 2-cyanothioacetamides},
journal = {Mendeleev Communications},
year = {2018},
volume = {29},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.01.022},
number = {1},
pages = {67--68},
doi = {10.1016/j.mencom.2019.01.022}
}
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Kornev, Mikhail Yur'evich, et al. “Reactions of chromone-3-carboxamides with 2-cyanothioacetamides.” Mendeleev Communications, vol. 29, no. 1, Dec. 2018, pp. 67-68. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2019.01.022.

Abstract

Chromone-3-carboxamides react with cyanothioacetamide in the presence of NaOEt in boiling ethanol to form 5-oxo-2-thioxo-1,5-dihydro-2H-chromeno[4,3-b]pyridine-3-carbonitriles (67–87% yields), whereas their reaction with N-methylcyanothioacetamide and a catalytic amount of Et3N in boiling ethanol affords 5-cyano-2-(2-hydroxyphenyl)-1-methyl-6-thioxo-1,6-dihydropyridine-3-carboxamides in 57–73% yields.

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