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Synthesis of hybrid structures comprising diaziridine and cyclopropane rings in one molecule

Vladimir Vladimirovich Kuznetsov 1
Vladimir Vladimirovich Kuznetsov
, 
Vadim Vadimovich Kachala 1
Vadim Vadimovich Kachala
, 
Nina Nikolaevna Makhova 1
Nina Nikolaevna Makhova
10.1016/j.mencom.2018.09.015
Published 2018-09-07
Communication , Volume 28, Issue 5, 497-500
11
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Kuznetsov V. V., Kachala V. V., Makhova N. N. Synthesis of hybrid structures comprising diaziridine and cyclopropane rings in one molecule // Mendeleev Communications. 2018. Vol. 28. No. 5. pp. 497-500.
GOST all authors (up to 50) Copy
Kuznetsov V. V., Kachala V. V., Makhova N. N. Synthesis of hybrid structures comprising diaziridine and cyclopropane rings in one molecule // Mendeleev Communications. 2018. Vol. 28. No. 5. pp. 497-500.
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TY - JOUR
DO - 10.1016/j.mencom.2018.09.015
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2018.09.015
TI - Synthesis of hybrid structures comprising diaziridine and cyclopropane rings in one molecule
T2 - Mendeleev Communications
AU - Kuznetsov, Vladimir Vladimirovich
AU - Kachala, Vadim Vadimovich
AU - Makhova, Nina Nikolaevna
PY - 2018
DA - 2018/09/07
PB - Mendeleev Communications
SP - 497-500
IS - 5
VL - 28
ER -
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@article{2018_Kuznetsov,
author = {Vladimir Vladimirovich Kuznetsov and Vadim Vadimovich Kachala and Nina Nikolaevna Makhova},
title = {Synthesis of hybrid structures comprising diaziridine and cyclopropane rings in one molecule},
journal = {Mendeleev Communications},
year = {2018},
volume = {28},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2018.09.015},
number = {5},
pages = {497--500},
doi = {10.1016/j.mencom.2018.09.015}
}
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Kuznetsov, Vladimir Vladimirovich, et al. “Synthesis of hybrid structures comprising diaziridine and cyclopropane rings in one molecule.” Mendeleev Communications, vol. 28, no. 5, Sep. 2018, pp. 497-500. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2018.09.015.

Abstract

A facile, diastereoselective method for the synthesis of diaziridines with C- and N-cyclopropyl substituents has been developed, N-cyclopropyldiaziridines being for the first time synthesized. The method is based on one-pot three-component condensation of cyclopropyl-containing carbonyl compounds, primary aliphatic amines including cyclopropylamine, and N-chloroalkylamines in organic solvents in the presence of bases under mild conditions.

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