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Synthesis of azacycloalkane-1,2-fused pyrroles via alkylation of cyclic ketimines with α-bromo ketones

Olga I Shmatova 1
Olga I Shmatova
, 
Valentin Georgievich Nenajdenko 1
Valentin Georgievich Nenajdenko
10.1016/j.mencom.2018.05.013
Published 2018-04-27
Communication , Volume 28, Issue 3, 270-271
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Shmatova O. I., Nenajdenko V. G. Synthesis of azacycloalkane-1,2-fused pyrroles via alkylation of cyclic ketimines with α-bromo ketones // Mendeleev Communications. 2018. Vol. 28. No. 3. pp. 270-271.
GOST all authors (up to 50) Copy
Shmatova O. I., Nenajdenko V. G. Synthesis of azacycloalkane-1,2-fused pyrroles via alkylation of cyclic ketimines with α-bromo ketones // Mendeleev Communications. 2018. Vol. 28. No. 3. pp. 270-271.
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TY - JOUR
DO - 10.1016/j.mencom.2018.05.013
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2018.05.013
TI - Synthesis of azacycloalkane-1,2-fused pyrroles via alkylation of cyclic ketimines with α-bromo ketones
T2 - Mendeleev Communications
AU - Shmatova, Olga I
AU - Nenajdenko, Valentin Georgievich
PY - 2018
DA - 2018/04/27
PB - Mendeleev Communications
SP - 270-271
IS - 3
VL - 28
ER -
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@article{2018_Shmatova,
author = {Olga I Shmatova and Valentin Georgievich Nenajdenko},
title = {Synthesis of azacycloalkane-1,2-fused pyrroles via alkylation of cyclic ketimines with α-bromo ketones},
journal = {Mendeleev Communications},
year = {2018},
volume = {28},
publisher = {Mendeleev Communications},
month = {Apr},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2018.05.013},
number = {3},
pages = {270--271},
doi = {10.1016/j.mencom.2018.05.013}
}
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Shmatova, Olga I., and Valentin Georgievich Nenajdenko. “Synthesis of azacycloalkane-1,2-fused pyrroles via alkylation of cyclic ketimines with α-bromo ketones.” Mendeleev Communications, vol. 28, no. 3, Apr. 2018, pp. 270-271. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2018.05.013.

Abstract

The reaction of 2-alkyl-substituted 5-, 6- and 7-membered cyclic imines with a-bromo ketones in the presence of Hünig's base affords 2,3-dihydro-1H-pyrrolizines, 5,6,7,8-tetrahydroindolizines and 6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]azepines, respectively.

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