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New selective cyclizations of alk-4-ynals with primary amines and azoles:one-pot synthesis of 2-azolylpyrrolidines and 3-iminocyclopentenes

Valentin Dmitrievich Gvozdev 1
Valentin Dmitrievich Gvozdev
, 
Konstantin Nikolaevich Shavrin 1
Konstantin Nikolaevich Shavrin
, 
Mikhail Petrovich Egorov 1
Mikhail Petrovich Egorov
, 
Oleg Matveevich Nefedov 1
Oleg Matveevich Nefedov
10.1016/j.mencom.2018.03.002
Published 2018-03-01
Communication , Volume 28, Issue 2, 123-125
2
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Gvozdev V. D. et al. New selective cyclizations of alk-4-ynals with primary amines and azoles:one-pot synthesis of 2-azolylpyrrolidines and 3-iminocyclopentenes // Mendeleev Communications. 2018. Vol. 28. No. 2. pp. 123-125.
GOST all authors (up to 50) Copy
Gvozdev V. D., Shavrin K. N., Egorov M. P., Nefedov O. M. New selective cyclizations of alk-4-ynals with primary amines and azoles:one-pot synthesis of 2-azolylpyrrolidines and 3-iminocyclopentenes // Mendeleev Communications. 2018. Vol. 28. No. 2. pp. 123-125.
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TY - JOUR
DO - 10.1016/j.mencom.2018.03.002
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2018.03.002
TI - New selective cyclizations of alk-4-ynals with primary amines and azoles:one-pot synthesis of 2-azolylpyrrolidines and 3-iminocyclopentenes
T2 - Mendeleev Communications
AU - Gvozdev, Valentin Dmitrievich
AU - Shavrin, Konstantin Nikolaevich
AU - Egorov, Mikhail Petrovich
AU - Nefedov, Oleg Matveevich
PY - 2018
DA - 2018/03/01
PB - Mendeleev Communications
SP - 123-125
IS - 2
VL - 28
ER -
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@article{2018_Gvozdev,
author = {Valentin Dmitrievich Gvozdev and Konstantin Nikolaevich Shavrin and Mikhail Petrovich Egorov and Oleg Matveevich Nefedov},
title = {New selective cyclizations of alk-4-ynals with primary amines and azoles:one-pot synthesis of 2-azolylpyrrolidines and 3-iminocyclopentenes},
journal = {Mendeleev Communications},
year = {2018},
volume = {28},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2018.03.002},
number = {2},
pages = {123--125},
doi = {10.1016/j.mencom.2018.03.002}
}
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Gvozdev, Valentin Dmitrievich, et al. “New selective cyclizations of alk-4-ynals with primary amines and azoles:one-pot synthesis of 2-azolylpyrrolidines and 3-iminocyclopentenes.” Mendeleev Communications, vol. 28, no. 2, Mar. 2018, pp. 123-125. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2018.03.002.

Abstract

One-pot cyclization of alk-4-ynals with primary aliphatic amines and azoles in DMSO under the action of KOH affords 1-alkyl-2-azolyl-5-arylmethylidenepyrrolidines. Similar processes with lithium monoalkylamides in THF give rise to 3-iminocyclopentenes.

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