Home / Publications / Halogenated (F, Cl) 1,3-benzodiazoles, 1,2,3-benzotriazoles, 2,1,3-benzothia(selena)diazoles and 1,4-benzodiazines inducing Hep2 cell apoptosis

Halogenated (F, Cl) 1,3-benzodiazoles, 1,2,3-benzotriazoles, 2,1,3-benzothia(selena)diazoles and 1,4-benzodiazines inducing Hep2 cell apoptosis

Darya Olegovna Prima 1, 2
Darya Olegovna Prima
, 
Elena Vladimirovna Vorontsova 3
Elena Vladimirovna Vorontsova
, 
Arkady Glebovich Makarov 1
Arkady Glebovich Makarov
, 
Alexander Yur'evich Makarov 1
Alexander Yur'evich Makarov
, 
Irina Yur'evna Bagryanskaya 1, 4
Irina Yur'evna Bagryanskaya
, 
Tatiana Fedorovna Mikhailovskaya 1
Tatiana Fedorovna Mikhailovskaya
, 
Yury Gennadievich Slizhov 2
Yury Gennadievich Slizhov
, 
Andrey Viktorovich Zibarev 1, 2
Andrey Viktorovich Zibarev
10.1016/j.mencom.2017.09.002
Published 2017-09-07
Communication , Volume 27, Issue 5, 439-442
23
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Prima D. O. et al. Halogenated (F, Cl) 1,3-benzodiazoles, 1,2,3-benzotriazoles, 2,1,3-benzothia(selena)diazoles and 1,4-benzodiazines inducing Hep2 cell apoptosis // Mendeleev Communications. 2017. Vol. 27. No. 5. pp. 439-442.
GOST all authors (up to 50) Copy
Prima D. O., Vorontsova E. V., Makarov A. G., Makarov A. Y., Bagryanskaya I. Y., Mikhailovskaya T. F., Slizhov Y. G., Zibarev A. V. Halogenated (F, Cl) 1,3-benzodiazoles, 1,2,3-benzotriazoles, 2,1,3-benzothia(selena)diazoles and 1,4-benzodiazines inducing Hep2 cell apoptosis // Mendeleev Communications. 2017. Vol. 27. No. 5. pp. 439-442.
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TY - JOUR
DO - 10.1016/j.mencom.2017.09.002
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2017.09.002
TI - Halogenated (F, Cl) 1,3-benzodiazoles, 1,2,3-benzotriazoles, 2,1,3-benzothia(selena)diazoles and 1,4-benzodiazines inducing Hep2 cell apoptosis
T2 - Mendeleev Communications
AU - Prima, Darya Olegovna
AU - Vorontsova, Elena Vladimirovna
AU - Makarov, Arkady Glebovich
AU - Makarov, Alexander Yur'evich
AU - Bagryanskaya, Irina Yur'evna
AU - Mikhailovskaya, Tatiana Fedorovna
AU - Slizhov, Yury Gennadievich
AU - Zibarev, Andrey Viktorovich
PY - 2017
DA - 2017/09/07
PB - Mendeleev Communications
SP - 439-442
IS - 5
VL - 27
ER -
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@article{2017_Prima,
author = {Darya Olegovna Prima and Elena Vladimirovna Vorontsova and Arkady Glebovich Makarov and Alexander Yur'evich Makarov and Irina Yur'evna Bagryanskaya and Tatiana Fedorovna Mikhailovskaya and Yury Gennadievich Slizhov and Andrey Viktorovich Zibarev},
title = {Halogenated (F, Cl) 1,3-benzodiazoles, 1,2,3-benzotriazoles, 2,1,3-benzothia(selena)diazoles and 1,4-benzodiazines inducing Hep2 cell apoptosis},
journal = {Mendeleev Communications},
year = {2017},
volume = {27},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2017.09.002},
number = {5},
pages = {439--442},
doi = {10.1016/j.mencom.2017.09.002}
}
MLA
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Prima, Darya Olegovna, et al. “Halogenated (F, Cl) 1,3-benzodiazoles, 1,2,3-benzotriazoles, 2,1,3-benzothia(selena)diazoles and 1,4-benzodiazines inducing Hep2 cell apoptosis.” Mendeleev Communications, vol. 27, no. 5, Sep. 2017, pp. 439-442. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2017.09.002.

Abstract

The title compounds synthesized from halogenated arene-1,2-diamines revealed, together with the latter, cytotoxicity towards the Hep2 (laryngeal epidermoid carcinoma) cells. The cytotoxicity was high and was accompanied by pronounced apoptotic activity at low concentrations for fluorinated diazoles, triazoles and selenadiazoles.

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