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Side-modified 15-deoxy-Δ12,14-prostaglandin D2, precursor of corresponding PGJ2. Synthesis from cloprostenol and anticancer activity

Nikolay Sergeyevich Vostrikov 1
Nikolay Sergeyevich Vostrikov
, 
Ilya Fedorovich Lobko 1
Ilya Fedorovich Lobko
, 
Leonid Vasilevich Spirikhin 1
Leonid Vasilevich Spirikhin
, 
Yulia Venerovna Vakhitova 2
Yulia Venerovna Vakhitova
, 
Kazimir Konstantinovich Pivnitsky 3
Kazimir Konstantinovich Pivnitsky
, 
Mansur Sagar'yarovich Miftakhov 1
Mansur Sagar'yarovich Miftakhov
10.1016/j.mencom.2017.03.005
Published 2017-02-27
Communication , Volume 27, Issue 2, 125-127
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Vostrikov N. S. et al. Side-modified 15-deoxy-Δ12,14-prostaglandin D2, precursor of corresponding PGJ2. Synthesis from cloprostenol and anticancer activity // Mendeleev Communications. 2017. Vol. 27. No. 2. pp. 125-127.
GOST all authors (up to 50) Copy
Vostrikov N. S., Lobko I. F., Spirikhin L. V., Vakhitova Y. V., Pivnitsky K. K., Miftakhov M. S. Side-modified 15-deoxy-Δ12,14-prostaglandin D2, precursor of corresponding PGJ2. Synthesis from cloprostenol and anticancer activity // Mendeleev Communications. 2017. Vol. 27. No. 2. pp. 125-127.
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TY - JOUR
DO - 10.1016/j.mencom.2017.03.005
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2017.03.005
TI - Side-modified 15-deoxy-Δ12,14-prostaglandin D2, precursor of corresponding PGJ2. Synthesis from cloprostenol and anticancer activity
T2 - Mendeleev Communications
AU - Vostrikov, Nikolay Sergeyevich
AU - Lobko, Ilya Fedorovich
AU - Spirikhin, Leonid Vasilevich
AU - Vakhitova, Yulia Venerovna
AU - Pivnitsky, Kazimir Konstantinovich
AU - Miftakhov, Mansur Sagar'yarovich
PY - 2017
DA - 2017/02/27
PB - Mendeleev Communications
SP - 125-127
IS - 2
VL - 27
ER -
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@article{2017_Vostrikov,
author = {Nikolay Sergeyevich Vostrikov and Ilya Fedorovich Lobko and Leonid Vasilevich Spirikhin and Yulia Venerovna Vakhitova and Kazimir Konstantinovich Pivnitsky and Mansur Sagar'yarovich Miftakhov},
title = {Side-modified 15-deoxy-Δ12,14-prostaglandin D2, precursor of corresponding PGJ2. Synthesis from cloprostenol and anticancer activity},
journal = {Mendeleev Communications},
year = {2017},
volume = {27},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2017.03.005},
number = {2},
pages = {125--127},
doi = {10.1016/j.mencom.2017.03.005}
}
MLA
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Vostrikov, Nikolay Sergeyevich, et al. “Side-modified 15-deoxy-Δ12,14-prostaglandin D2, precursor of corresponding PGJ2. Synthesis from cloprostenol and anticancer activity.” Mendeleev Communications, vol. 27, no. 2, Feb. 2017, pp. 125-127. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2017.03.005.

Abstract

The title compound, a possible precursor of metabolically stable corresponding PGJ2, was obtained from cloprostenol in seven steps. The compound demonstrated cytotoxicity against the HEK 293, Hep G2 and Jurkat cell lines.

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