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The first total synthesis of lembehyne B

Vladimir Anatol'evich D'yakonov 1
Vladimir Anatol'evich D'yakonov
, 
Aleksey Aleksandrovich Makarov 1
Aleksey Aleksandrovich Makarov
, 
Lilya Useinovna Dzhemileva 1
Lilya Useinovna Dzhemileva
, 
Evgeny Nazarovich Andreev 1
Evgeny Nazarovich Andreev
, 
10.1016/j.mencom.2017.03.004
Published 2017-02-27
Communication , Volume 27, Issue 2, 122-124
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D'yakonov V. A. et al. The first total synthesis of lembehyne B // Mendeleev Communications. 2017. Vol. 27. No. 2. pp. 122-124.
GOST all authors (up to 50) Copy
D'yakonov V. A., Makarov A. A., Dzhemileva L. U., Andreev E. N., Dzhemilev U. M. The first total synthesis of lembehyne B // Mendeleev Communications. 2017. Vol. 27. No. 2. pp. 122-124.
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TY - JOUR
DO - 10.1016/j.mencom.2017.03.004
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2017.03.004
TI - The first total synthesis of lembehyne B
T2 - Mendeleev Communications
AU - D'yakonov, Vladimir Anatol'evich
AU - Makarov, Aleksey Aleksandrovich
AU - Dzhemileva, Lilya Useinovna
AU - Andreev, Evgeny Nazarovich
AU - Dzhemilev, Usein Memetovich
PY - 2017
DA - 2017/02/27
PB - Mendeleev Communications
SP - 122-124
IS - 2
VL - 27
ER -
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@article{2017_D'yakonov,
author = {Vladimir Anatol'evich D'yakonov and Aleksey Aleksandrovich Makarov and Lilya Useinovna Dzhemileva and Evgeny Nazarovich Andreev and Usein Memetovich Dzhemilev},
title = {The first total synthesis of lembehyne B},
journal = {Mendeleev Communications},
year = {2017},
volume = {27},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2017.03.004},
number = {2},
pages = {122--124},
doi = {10.1016/j.mencom.2017.03.004}
}
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D'yakonov, Vladimir Anatol'evich, et al. “The first total synthesis of lembehyne B.” Mendeleev Communications, vol. 27, no. 2, Feb. 2017, pp. 122-124. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2017.03.004.

Abstract

The total synthesis of lembehyne B was accomplished in five steps in 51% total yield. The cross-cyclomagnesiation of two allenic components, nonadeca-1,2-diene and pentadeca-13,14-dien-1-ol tetrahydropyranyl ether, with EtMgBr in the presence of Mg and Cp2TiCl2 catalyst (10 mol%) was used in the key step of the synthesis.

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