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Tandem AN–AN reactions in the synthesis of tetrahydrothiazolo[4,5-e][1,2,4]triazines

Nataliya Nikolaevna Mochulskaya 1, 2
Nataliya Nikolaevna Mochulskaya
, 
Pavel Alexandrovich Slepukhin 1, 2
Pavel Alexandrovich Slepukhin
, 
Valery Nikolaevich Charushin 1, 2
Valery Nikolaevich Charushin
, 
Mikhail Isaakovich Kodess 1, 2
Mikhail Isaakovich Kodess
10.1016/j.mencom.2016.09.002
Published 2016-09-08
Communication , Volume 26, Issue 5, 375-377
3
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Mochulskaya N. N. et al. Tandem AN–AN reactions in the synthesis of tetrahydrothiazolo[4,5-e][1,2,4]triazines // Mendeleev Communications. 2016. Vol. 26. No. 5. pp. 375-377.
GOST all authors (up to 50) Copy
Mochulskaya N. N., Slepukhin P. A., Charushin V. N., Kodess M. I. Tandem AN–AN reactions in the synthesis of tetrahydrothiazolo[4,5-e][1,2,4]triazines // Mendeleev Communications. 2016. Vol. 26. No. 5. pp. 375-377.
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TY - JOUR
DO - 10.1016/j.mencom.2016.09.002
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2016.09.002
TI - Tandem AN–AN reactions in the synthesis of tetrahydrothiazolo[4,5-e][1,2,4]triazines
T2 - Mendeleev Communications
AU - Mochulskaya, Nataliya Nikolaevna
AU - Slepukhin, Pavel Alexandrovich
AU - Charushin, Valery Nikolaevich
AU - Kodess, Mikhail Isaakovich
PY - 2016
DA - 2016/09/08
PB - Mendeleev Communications
SP - 375-377
IS - 5
VL - 26
ER -
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@article{2016_Mochulskaya,
author = {Nataliya Nikolaevna Mochulskaya and Pavel Alexandrovich Slepukhin and Valery Nikolaevich Charushin and Mikhail Isaakovich Kodess},
title = {Tandem AN–AN reactions in the synthesis of tetrahydrothiazolo[4,5-e][1,2,4]triazines},
journal = {Mendeleev Communications},
year = {2016},
volume = {26},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2016.09.002},
number = {5},
pages = {375--377},
doi = {10.1016/j.mencom.2016.09.002}
}
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Mochulskaya, Nataliya Nikolaevna, et al. “Tandem AN–AN reactions in the synthesis of tetrahydrothiazolo[4,5-e][1,2,4]triazines.” Mendeleev Communications, vol. 26, no. 5, Sep. 2016, pp. 375-377. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2016.09.002.

Abstract

Reaction of 3-aryl-1,2,4-triazines with S,N-dinucleophilic N-(het)arylthioureas in acetic anhydride at room temperature affords the cyclization products, tetrahydrothiazolo[4,5-e]-[1,2,4]triazines in good yields. The structure of the heterocyclic system thus formed was confirmed by X-ray diffraction analysis.

References

1.
10.1016/j.mencom.2016.09.002_bib0005
2014
3.
10.1016/j.mencom.2016.09.002_bib0015
Chupakhin
Nucleophilic Aromatic Substitution of Hydrogen, 1994
4.
Behavior of Monocyclic 1,2,4-Triazines in Reactions with C-, N-, O-, and S-Nucleophiles
Charushin V.N., Alexeev S.G., Chupahkin O.N., Van Der Plas H.C.
Advances in Heterocyclic Chemistry, 1989
5.
N. Chupakhin O., Chupakhin O., Alexeev S., Rudakov B., Charushin V.
Heterocycles, 1992
7.
Rusinov G.L., Slepukhin P.A., Charushin V.N., Dyachenko O.A., Kazheva O.N., Chekhlov A.N., Verbitsky E.V., Kodess M.I., Chupakhin O.N.
Mendeleev Communications, 2006
8.
Charushinx V.N., Mochulskaya N.N., Andreiko A.A., Kodess M.I., Chupakhin O.N.
Mendeleev Communications, 2002
9.
Annelation of the thiazole ring to 1,2,4-triazines by tandem AN—ANor SNH—SNHreactions
Mochul"skaya N.N., Andreiko A.A., Kodess M.I., Vasil"eva E.B., Filyakova V.I., Gubaidullin A.T., Litvinov I.A., Sinyashin O.G., Aleksandrov G.G., Charushin V.N.
Russian Chemical Bulletin, 2004
10.
A simple one pot synthesis of condensed 1,2,4-triazines by using the tandem aN-SNipsoand SNH-SNipsareactions
Chupakhin O.N., Rusinov G.L., Beresnev D.G., Charushin V.N., Neunhoeffer H.
Journal of Heterocyclic Chemistry, 2001
11.
Application of 1H, 13C and 15N NMR in the chemistry of 1,4-diazines
Chupakhin O.N., Charushin V.N., Chernyshev A.I.
Progress in Nuclear Magnetic Resonance Spectroscopy, 1988
12.
V. N. Charushin, Dr. Sci. Thesis, Sverdlovsk, 1984.
13.
10.1016/j.mencom.2016.09.002_bib0065
Charushin
2008
14.
A short history of SHELX
Sheldrick G.M.
Acta Crystallographica Section A Foundations of Crystallography, 2007