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Highly efficient one-pot cascade cyclization of 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles into spirocyclopropyl pyrazolones

Anatoly Nikolaevich Vereshchagin 1
Anatoly Nikolaevich Vereshchagin
,  , 
Alexander Dmitrievich Korshunov 1
Alexander Dmitrievich Korshunov
, 
Mikhail Petrovich Egorov 1
Mikhail Petrovich Egorov
10.1016/j.mencom.2016.01.008
Published 2015-12-30
Communication , Volume 26, Issue 1, 19-20
5
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Vereshchagin A. N. et al. Highly efficient one-pot cascade cyclization of 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles into spirocyclopropyl pyrazolones // Mendeleev Communications. 2015. Vol. 26. No. 1. pp. 19-20.
GOST all authors (up to 50) Copy
Vereshchagin A. N., Elinson M. N., Korshunov A. D., Egorov M. P. Highly efficient one-pot cascade cyclization of 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles into spirocyclopropyl pyrazolones // Mendeleev Communications. 2015. Vol. 26. No. 1. pp. 19-20.
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TY - JOUR
DO - 10.1016/j.mencom.2016.01.008
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2016.01.008
TI - Highly efficient one-pot cascade cyclization of 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles into spirocyclopropyl pyrazolones
T2 - Mendeleev Communications
AU - Vereshchagin, Anatoly Nikolaevich
AU - Elinson, Michail Nikolaevich
AU - Korshunov, Alexander Dmitrievich
AU - Egorov, Mikhail Petrovich
PY - 2015
DA - 2015/12/30
PB - Mendeleev Communications
SP - 19-20
IS - 1
VL - 26
ER -
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@article{2015_Vereshchagin,
author = {Anatoly Nikolaevich Vereshchagin and Michail Nikolaevich Elinson and Alexander Dmitrievich Korshunov and Mikhail Petrovich Egorov},
title = {Highly efficient one-pot cascade cyclization of 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles into spirocyclopropyl pyrazolones},
journal = {Mendeleev Communications},
year = {2015},
volume = {26},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2016.01.008},
number = {1},
pages = {19--20},
doi = {10.1016/j.mencom.2016.01.008}
}
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Vereshchagin, Anatoly Nikolaevich, et al. “Highly efficient one-pot cascade cyclization of 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles into spirocyclopropyl pyrazolones.” Mendeleev Communications, vol. 26, no. 1, Dec. 2015, pp. 19-20. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2016.01.008.

Abstract

Bromine-assisted one-pot cascade cyclization of 3-(5-hydroxy-3-methylpyrazol-4-yl)-3-arylpropionitriles affords medicinally relevant spirocyclopropyl pyrazolones in 60–97% yields.

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