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How sensitive and accurate are routine NMR and MS measurements?

Andrey Mikhailovich Tsedilin 1
Andrey Mikhailovich Tsedilin
, 
Artem Nikolaevich Fakhrutdinov 1
Artem Nikolaevich Fakhrutdinov
,  , 
Sergey Sergeyevich Zalesskiy 1
Sergey Sergeyevich Zalesskiy
, 
Alexander Olegovich Chizhov 1
Alexander Olegovich Chizhov
, 
Natal'ya Georgievna Kolotyrkina 1
Natal'ya Georgievna Kolotyrkina
, 
10.1016/j.mencom.2015.11.019
Published 2015-11-09
Communication , Volume 25, Issue 6, 454-456
118
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Tsedilin A. M. et al. How sensitive and accurate are routine NMR and MS measurements? // Mendeleev Communications. 2015. Vol. 25. No. 6. pp. 454-456.
GOST all authors (up to 50) Copy
Tsedilin A. M., Fakhrutdinov A. N., Eremin D. B., Zalesskiy S. S., Chizhov A. O., Kolotyrkina N. G., Ananikov V. P. How sensitive and accurate are routine NMR and MS measurements? // Mendeleev Communications. 2015. Vol. 25. No. 6. pp. 454-456.
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TY - JOUR
DO - 10.1016/j.mencom.2015.11.019
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.11.019
TI - How sensitive and accurate are routine NMR and MS measurements?
T2 - Mendeleev Communications
AU - Tsedilin, Andrey Mikhailovich
AU - Fakhrutdinov, Artem Nikolaevich
AU - Eremin, Dmitrii Borisovich
AU - Zalesskiy, Sergey Sergeyevich
AU - Chizhov, Alexander Olegovich
AU - Kolotyrkina, Natal'ya Georgievna
AU - Ananikov, Valentin Pavlovich
PY - 2015
DA - 2015/11/09
PB - Mendeleev Communications
SP - 454-456
IS - 6
VL - 25
ER -
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@article{2015_Tsedilin,
author = {Andrey Mikhailovich Tsedilin and Artem Nikolaevich Fakhrutdinov and Dmitrii Borisovich Eremin and Sergey Sergeyevich Zalesskiy and Alexander Olegovich Chizhov and Natal'ya Georgievna Kolotyrkina and Valentin Pavlovich Ananikov},
title = {How sensitive and accurate are routine NMR and MS measurements?},
journal = {Mendeleev Communications},
year = {2015},
volume = {25},
publisher = {Mendeleev Communications},
month = {Nov},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.11.019},
number = {6},
pages = {454--456},
doi = {10.1016/j.mencom.2015.11.019}
}
MLA
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MLA Copy
Tsedilin, Andrey Mikhailovich, et al. “How sensitive and accurate are routine NMR and MS measurements?.” Mendeleev Communications, vol. 25, no. 6, Nov. 2015, pp. 454-456. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.11.019.

Abstract

The necessary prerequisites to carry out efficient NMR/MS studies and the important points required to avoid inconsistent measurements are discussed. A comparative assessment of the sensitivity and accuracy of NMR, EI-MS and ESI-MS measurements was carried out to evaluate typical laboratory research performance. Accurate NMR measurements are possible in the 10–1–10–3 M concentration range, with spectral studies still being possible at concentrations of approximately 10–4–10–5 M. EI-MS is more sensitive and can operate at concentrations of 10–6 M, while commonly available ESI-MS can be efficient up to a concentration of 10–18 M.

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