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Computational study of the possible formation of the ternary complex between thrombin, antithrombin III and fucosylated chondroitin sulfates

Alexey Genrikhovich Gerbst 1
Alexey Genrikhovich Gerbst
, 
Nadezhda Evgenievna Ustyuzhanina 1
Nadezhda Evgenievna Ustyuzhanina
, 
Nikolay Eduardovich Nifantiev 1
Nikolay Eduardovich Nifantiev
10.1016/j.mencom.2015.11.006
Published 2015-11-09
Communication , Volume 25, Issue 6, 420-421
8
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Gerbst A. G., Ustyuzhanina N. E., Nifantiev N. E. Computational study of the possible formation of the ternary complex between thrombin, antithrombin III and fucosylated chondroitin sulfates // Mendeleev Communications. 2015. Vol. 25. No. 6. pp. 420-421.
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Gerbst A. G., Ustyuzhanina N. E., Nifantiev N. E. Computational study of the possible formation of the ternary complex between thrombin, antithrombin III and fucosylated chondroitin sulfates // Mendeleev Communications. 2015. Vol. 25. No. 6. pp. 420-421.
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TY - JOUR
DO - 10.1016/j.mencom.2015.11.006
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.11.006
TI - Computational study of the possible formation of the ternary complex between thrombin, antithrombin III and fucosylated chondroitin sulfates
T2 - Mendeleev Communications
AU - Gerbst, Alexey Genrikhovich
AU - Ustyuzhanina, Nadezhda Evgenievna
AU - Nifantiev, Nikolay Eduardovich
PY - 2015
DA - 2015/11/09
PB - Mendeleev Communications
SP - 420-421
IS - 6
VL - 25
ER -
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@article{2015_Gerbst,
author = {Alexey Genrikhovich Gerbst and Nadezhda Evgenievna Ustyuzhanina and Nikolay Eduardovich Nifantiev},
title = {Computational study of the possible formation of the ternary complex between thrombin, antithrombin III and fucosylated chondroitin sulfates},
journal = {Mendeleev Communications},
year = {2015},
volume = {25},
publisher = {Mendeleev Communications},
month = {Nov},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.11.006},
number = {6},
pages = {420--421},
doi = {10.1016/j.mencom.2015.11.006}
}
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Gerbst, Alexey Genrikhovich, et al. “Computational study of the possible formation of the ternary complex between thrombin, antithrombin III and fucosylated chondroitin sulfates.” Mendeleev Communications, vol. 25, no. 6, Nov. 2015, pp. 420-421. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.11.006.

Abstract

Computer docking studies suggest an explanation for better anticoagulant activity of fucosylated chondroitin sulfates as compared to non-fucosylated ones due to the formation of the ternary complex with thrombin and antithrombin III.

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