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A facile synthesis of regioisomeric 4-amino- and 6-amino-3-arylpyrazolo[3,4-b]pyridine-5-carbonitriles

P A Petrov 1
P A Petrov
, 
Alexander Nikolaevich Kasatochkin 1
Alexander Nikolaevich Kasatochkin
, 
Stanislav Ivanovich Selivanov 1
Stanislav Ivanovich Selivanov
10.1016/j.mencom.2015.09.023
Published 2015-09-10
Communication , Volume 25, Issue 5, 382-383
4
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Petrov P. A., Kasatochkin A. N., Selivanov S. I. A facile synthesis of regioisomeric 4-amino- and 6-amino-3-arylpyrazolo[3,4-b]pyridine-5-carbonitriles // Mendeleev Communications. 2015. Vol. 25. No. 5. pp. 382-383.
GOST all authors (up to 50) Copy
Petrov P. A., Kasatochkin A. N., Selivanov S. I. A facile synthesis of regioisomeric 4-amino- and 6-amino-3-arylpyrazolo[3,4-b]pyridine-5-carbonitriles // Mendeleev Communications. 2015. Vol. 25. No. 5. pp. 382-383.
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TY - JOUR
DO - 10.1016/j.mencom.2015.09.023
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.09.023
TI - A facile synthesis of regioisomeric 4-amino- and 6-amino-3-arylpyrazolo[3,4-b]pyridine-5-carbonitriles
T2 - Mendeleev Communications
AU - Petrov, P A
AU - Kasatochkin, Alexander Nikolaevich
AU - Selivanov, Stanislav Ivanovich
PY - 2015
DA - 2015/09/10
PB - Mendeleev Communications
SP - 382-383
IS - 5
VL - 25
ER -
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@article{2015_Petrov,
author = {P A Petrov and Alexander Nikolaevich Kasatochkin and Stanislav Ivanovich Selivanov},
title = {A facile synthesis of regioisomeric 4-amino- and 6-amino-3-arylpyrazolo[3,4-b]pyridine-5-carbonitriles},
journal = {Mendeleev Communications},
year = {2015},
volume = {25},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.09.023},
number = {5},
pages = {382--383},
doi = {10.1016/j.mencom.2015.09.023}
}
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Petrov, P. A., et al. “A facile synthesis of regioisomeric 4-amino- and 6-amino-3-arylpyrazolo[3,4-b]pyridine-5-carbonitriles.” Mendeleev Communications, vol. 25, no. 5, Sep. 2015, pp. 382-383. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.09.023.

Abstract

Boiling of 3-aryl-1-R-1H-pyrazol-5-amines with ethoxymethylidenemalononitrile in butanol affords 6-amino-3-aryl-1-R-1H-pyrazolo-[3,4-b]pyridine-5-carbonitriles, whereas low temperature condensation of the same reactants followed by heating to 230°C in diphenyl ether gives the isomeric 4-amino derivatives.

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