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Synthesis of glycoprotein N-chain core fragment GlcNAcβ1-4(Fucα1-6)GlcNAc

Galina Valentinovna Pazynina 1
Galina Valentinovna Pazynina
Svetlana Vladimirovna Tsygankova 1
Svetlana Vladimirovna Tsygankova
Published 2015-07-08
CommunicationVolume 25, Issue 4, 250-251
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Pazynina G. V., Tsygankova S. V., Bovin N. V. Synthesis of glycoprotein N-chain core fragment GlcNAcβ1-4(Fucα1-6)GlcNAc // Mendeleev Communications. 2015. Vol. 25. No. 4. pp. 250-251.
GOST all authors (up to 50) Copy
Pazynina G. V., Tsygankova S. V., Bovin N. V. Synthesis of glycoprotein N-chain core fragment GlcNAcβ1-4(Fucα1-6)GlcNAc // Mendeleev Communications. 2015. Vol. 25. No. 4. pp. 250-251.
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TY - JOUR
DO - 10.1016/j.mencom.2015.07.004
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.07.004
TI - Synthesis of glycoprotein N-chain core fragment GlcNAcβ1-4(Fucα1-6)GlcNAc
T2 - Mendeleev Communications
AU - Pazynina, Galina Valentinovna
AU - Tsygankova, Svetlana Vladimirovna
AU - Bovin, Nicolai Vladimirovich
PY - 2015
DA - 2015/07/08
PB - Mendeleev Communications
SP - 250-251
IS - 4
VL - 25
ER -
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@article{2015_Pazynina,
author = {Galina Valentinovna Pazynina and Svetlana Vladimirovna Tsygankova and Nicolai Vladimirovich Bovin},
title = {Synthesis of glycoprotein N-chain core fragment GlcNAcβ1-4(Fucα1-6)GlcNAc},
journal = {Mendeleev Communications},
year = {2015},
volume = {25},
publisher = {Mendeleev Communications},
month = {Jul},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.07.004},
number = {4},
pages = {250--251},
doi = {10.1016/j.mencom.2015.07.004}
}
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Pazynina, Galina Valentinovna, et al. “Synthesis of glycoprotein N-chain core fragment GlcNAcβ1-4(Fucα1-6)GlcNAc.” Mendeleev Communications, vol. 25, no. 4, Jul. 2015, pp. 250-251. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.07.004.

Abstract

Synthesis of Ac3GlcNAcβ(1-4)-3-Ac-6-BnGlcNTrocβ-O(CH2)3NHCOCF3, a convenient precursor for the preparation of 6-substituted derivatives of disaccharide GlcNAcβ1-4GlcNAc, is described. α-Fucosylation of this precursor after the removal of protection groups leads to the title trisaccharide, whereas O-sulfation results in 6-O-sulfated derivative of chitobiose.

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