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Synthesis of diethyl (aryl)(4-oxopiperidin-1-yl)methylphosphonates

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Evgenii A Skvortsov 1
Evgenii A Skvortsov
, 
10.1016/j.mencom.2015.05.026
Published 2015-04-28
Communication , Volume 25, Issue 3, 232-233
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Makarov M. V., Skvortsov E. A., Brel V. K. Synthesis of diethyl (aryl)(4-oxopiperidin-1-yl)methylphosphonates // Mendeleev Communications. 2015. Vol. 25. No. 3. pp. 232-233.
GOST all authors (up to 50) Copy
Makarov M. V., Skvortsov E. A., Brel V. K. Synthesis of diethyl (aryl)(4-oxopiperidin-1-yl)methylphosphonates // Mendeleev Communications. 2015. Vol. 25. No. 3. pp. 232-233.
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TY - JOUR
DO - 10.1016/j.mencom.2015.05.026
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.05.026
TI - Synthesis of diethyl (aryl)(4-oxopiperidin-1-yl)methylphosphonates
T2 - Mendeleev Communications
AU - Makarov, Mikhail Viktorovich
AU - Skvortsov, Evgenii A
AU - Brel, Valery Kuzmich
PY - 2015
DA - 2015/04/28
PB - Mendeleev Communications
SP - 232-233
IS - 3
VL - 25
ER -
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@article{2015_Makarov,
author = {Mikhail Viktorovich Makarov and Evgenii A Skvortsov and Valery Kuzmich Brel},
title = {Synthesis of diethyl (aryl)(4-oxopiperidin-1-yl)methylphosphonates},
journal = {Mendeleev Communications},
year = {2015},
volume = {25},
publisher = {Mendeleev Communications},
month = {Apr},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.05.026},
number = {3},
pages = {232--233},
doi = {10.1016/j.mencom.2015.05.026}
}
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Makarov, Mikhail Viktorovich, et al. “Synthesis of diethyl (aryl)(4-oxopiperidin-1-yl)methylphosphonates.” Mendeleev Communications, vol. 25, no. 3, Apr. 2015, pp. 232-233. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.05.026.

Abstract

The Kabachnik–Fields reaction of 4-piperidone hydrochloride monohydrate, an aromatic aldehyde and triethyl phosphite in the presence of triethylamine and magnesium perchlorate affords diethyl (aryl)(4-oxopiperidin-1-yl)methylphosphonates in moderate yields.

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