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Base-catalyzed α-vinylation of ketones with acetylenes as a key step in one-pot synthesis of pyrazolines and pyrazoles

Elena Yur'evna Schmidt 1
Elena Yur'evna Schmidt
, 
Elena V Ivanova 1
Elena V Ivanova
, 
Nadezhda Victorovna Semenova 1
Nadezhda Victorovna Semenova
, 
Inna Valeryevna Tatarinova 1
Inna Valeryevna Tatarinova
, 
Igor Alekseevich Ushakov 1
Igor Alekseevich Ushakov
, 
Boris Aleksandrovich Trofimov 1
Boris Aleksandrovich Trofimov
10.1016/j.mencom.2015.03.018
Published 2015-03-06
Communication , Volume 25, Issue 2, 131-132
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Schmidt E. Y. et al. Base-catalyzed α-vinylation of ketones with acetylenes as a key step in one-pot synthesis of pyrazolines and pyrazoles // Mendeleev Communications. 2015. Vol. 25. No. 2. pp. 131-132.
GOST all authors (up to 50) Copy
Schmidt E. Y., Ivanova E. V., Semenova N. V., Tatarinova I. V., Ushakov I. A., Trofimov B. A. Base-catalyzed α-vinylation of ketones with acetylenes as a key step in one-pot synthesis of pyrazolines and pyrazoles // Mendeleev Communications. 2015. Vol. 25. No. 2. pp. 131-132.
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TY - JOUR
DO - 10.1016/j.mencom.2015.03.018
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.03.018
TI - Base-catalyzed α-vinylation of ketones with acetylenes as a key step in one-pot synthesis of pyrazolines and pyrazoles
T2 - Mendeleev Communications
AU - Schmidt, Elena Yur'evna
AU - Ivanova, Elena V
AU - Semenova, Nadezhda Victorovna
AU - Tatarinova, Inna Valeryevna
AU - Ushakov, Igor Alekseevich
AU - Trofimov, Boris Aleksandrovich
PY - 2015
DA - 2015/03/06
PB - Mendeleev Communications
SP - 131-132
IS - 2
VL - 25
ER -
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@article{2015_Schmidt,
author = {Elena Yur'evna Schmidt and Elena V Ivanova and Nadezhda Victorovna Semenova and Inna Valeryevna Tatarinova and Igor Alekseevich Ushakov and Boris Aleksandrovich Trofimov},
title = {Base-catalyzed α-vinylation of ketones with acetylenes as a key step in one-pot synthesis of pyrazolines and pyrazoles},
journal = {Mendeleev Communications},
year = {2015},
volume = {25},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.03.018},
number = {2},
pages = {131--132},
doi = {10.1016/j.mencom.2015.03.018}
}
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Schmidt, Elena Yur'evna, et al. “Base-catalyzed α-vinylation of ketones with acetylenes as a key step in one-pot synthesis of pyrazolines and pyrazoles.” Mendeleev Communications, vol. 25, no. 2, Mar. 2015, pp. 131-132. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2015.03.018.

Abstract

The sequential reaction of ketones with phenylacetylene in the presence of KOH/DMSO system followed by the treatment of the reaction mixture with HCl and monosubstituted hydrazines leads to pyrazolines and pyrazoles in up to 87% total yield.

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