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Synthesis of the C6–C21 fragment of epothilone analogues

Ruslan Faridovich Valeev 1
Ruslan Faridovich Valeev
, 
Radmir Fatikhovich Bikzhanov 1
Radmir Fatikhovich Bikzhanov
, 
Mansur Sagar'yarovich Miftakhov 1
Mansur Sagar'yarovich Miftakhov
10.1016/j.mencom.2014.11.022
Published 2014-10-30
Communication , Volume 24, Issue 6, 372-373
6
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Valeev R. F., Bikzhanov R. F., Miftakhov M. S. Synthesis of the C6–C21 fragment of epothilone analogues // Mendeleev Communications. 2014. Vol. 24. No. 6. pp. 372-373.
GOST all authors (up to 50) Copy
Valeev R. F., Bikzhanov R. F., Miftakhov M. S. Synthesis of the C6–C21 fragment of epothilone analogues // Mendeleev Communications. 2014. Vol. 24. No. 6. pp. 372-373.
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TY - JOUR
DO - 10.1016/j.mencom.2014.11.022
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2014.11.022
TI - Synthesis of the C6–C21 fragment of epothilone analogues
T2 - Mendeleev Communications
AU - Valeev, Ruslan Faridovich
AU - Bikzhanov, Radmir Fatikhovich
AU - Miftakhov, Mansur Sagar'yarovich
PY - 2014
DA - 2014/10/30
PB - Mendeleev Communications
SP - 372-373
IS - 6
VL - 24
ER -
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@article{2014_Valeev,
author = {Ruslan Faridovich Valeev and Radmir Fatikhovich Bikzhanov and Mansur Sagar'yarovich Miftakhov},
title = {Synthesis of the C6–C21 fragment of epothilone analogues},
journal = {Mendeleev Communications},
year = {2014},
volume = {24},
publisher = {Mendeleev Communications},
month = {Oct},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2014.11.022},
number = {6},
pages = {372--373},
doi = {10.1016/j.mencom.2014.11.022}
}
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Valeev, Ruslan Faridovich, et al. “Synthesis of the C6–C21 fragment of epothilone analogues.” Mendeleev Communications, vol. 24, no. 6, Oct. 2014, pp. 372-373. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2014.11.022.

Abstract

(2S,4E,6Z,9S,10E)-9-[tert-Butyl(diphenyl)silyloxymethyl]-2,6,10-trimethyl-11-(2-methylthiazol-4-yl)undeca-4,6,10-trien-1-ol, a key precursor for epothilone analogues, was prepared by multi-step synthesis using the Julia–Kocienski olefination at the key step.

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