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Sodium acetate catalyzed multicomponent approach to medicinally privileged 2-amino-4H-chromene scaffold from salicylaldehydes, malononitrile and cyanoacetates

, 
Fedor Vladimirovich Ryzhkov 1
Fedor Vladimirovich Ryzhkov
, 
Ruslan Fedorovich Nasybullin 1
Ruslan Fedorovich Nasybullin
, 
Tatiana Aleksandrovna Zaimovskaya 2
Tatiana Aleksandrovna Zaimovskaya
, 
Mikhail Petrovich Egorov 1
Mikhail Petrovich Egorov
10.1016/j.mencom.2014.04.016
Published 2014-04-16
Communication , Volume 24, Issue 3, 170-172
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Elinson M. N. et al. Sodium acetate catalyzed multicomponent approach to medicinally privileged 2-amino-4H-chromene scaffold from salicylaldehydes, malononitrile and cyanoacetates // Mendeleev Communications. 2014. Vol. 24. No. 3. pp. 170-172.
GOST all authors (up to 50) Copy
Elinson M. N., Ryzhkov F. V., Nasybullin R. F., Zaimovskaya T. A., Egorov M. P. Sodium acetate catalyzed multicomponent approach to medicinally privileged 2-amino-4H-chromene scaffold from salicylaldehydes, malononitrile and cyanoacetates // Mendeleev Communications. 2014. Vol. 24. No. 3. pp. 170-172.
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TY - JOUR
DO - 10.1016/j.mencom.2014.04.016
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2014.04.016
TI - Sodium acetate catalyzed multicomponent approach to medicinally privileged 2-amino-4H-chromene scaffold from salicylaldehydes, malononitrile and cyanoacetates
T2 - Mendeleev Communications
AU - Elinson, Michail Nikolaevich
AU - Ryzhkov, Fedor Vladimirovich
AU - Nasybullin, Ruslan Fedorovich
AU - Zaimovskaya, Tatiana Aleksandrovna
AU - Egorov, Mikhail Petrovich
PY - 2014
DA - 2014/04/16
PB - Mendeleev Communications
SP - 170-172
IS - 3
VL - 24
ER -
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@article{2014_Elinson,
author = {Michail Nikolaevich Elinson and Fedor Vladimirovich Ryzhkov and Ruslan Fedorovich Nasybullin and Tatiana Aleksandrovna Zaimovskaya and Mikhail Petrovich Egorov},
title = {Sodium acetate catalyzed multicomponent approach to medicinally privileged 2-amino-4H-chromene scaffold from salicylaldehydes, malononitrile and cyanoacetates},
journal = {Mendeleev Communications},
year = {2014},
volume = {24},
publisher = {Mendeleev Communications},
month = {Apr},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2014.04.016},
number = {3},
pages = {170--172},
doi = {10.1016/j.mencom.2014.04.016}
}
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Elinson, Michail Nikolaevich, et al. “Sodium acetate catalyzed multicomponent approach to medicinally privileged 2-amino-4H-chromene scaffold from salicylaldehydes, malononitrile and cyanoacetates.” Mendeleev Communications, vol. 24, no. 3, Apr. 2014, pp. 170-172. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2014.04.016.

Abstract

Sodium acetate-catalyzed multicomponent assembling of salicylaldehydes, malononitrile and cyanoacetates in water–alcohol mixture (1: 1) at ambient temperature affords alkyl (2-amino-3-cyano-4H-chromen-4-yl)cyanoacetates in 88–95% yields.

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