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Synthesis of 2-(buta-1,3-diynyl)-N,N-dimethylanilines Using Reductive Methylation Step

Alexandra Evgenievna Kulyashova 1
Alexandra Evgenievna Kulyashova
, 
Elena V Mikheeva 1
Elena V Mikheeva
, 
Natalya A Danilkina 1
Natalya A Danilkina
, 
Irina Anatol'evna Balova 1
Irina Anatol'evna Balova
10.1016/j.mencom.2014.03.013
Published 2014-02-21
Communication , Volume 24, Issue 2, 102-104
4
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Kulyashova A. E. et al. Synthesis of 2-(buta-1,3-diynyl)-N,N-dimethylanilines Using Reductive Methylation Step // Mendeleev Communications. 2014. Vol. 24. No. 2. pp. 102-104.
GOST all authors (up to 50) Copy
Kulyashova A. E., Mikheeva E. V., Danilkina N. A., Balova I. A. Synthesis of 2-(buta-1,3-diynyl)-N,N-dimethylanilines Using Reductive Methylation Step // Mendeleev Communications. 2014. Vol. 24. No. 2. pp. 102-104.
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TY - JOUR
DO - 10.1016/j.mencom.2014.03.013
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2014.03.013
TI - Synthesis of 2-(buta-1,3-diynyl)-N,N-dimethylanilines Using Reductive Methylation Step
T2 - Mendeleev Communications
AU - Kulyashova, Alexandra Evgenievna
AU - Mikheeva, Elena V
AU - Danilkina, Natalya A
AU - Balova, Irina Anatol'evna
PY - 2014
DA - 2014/02/21
PB - Mendeleev Communications
SP - 102-104
IS - 2
VL - 24
ER -
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@article{2014_Kulyashova,
author = {Alexandra Evgenievna Kulyashova and Elena V Mikheeva and Natalya A Danilkina and Irina Anatol'evna Balova},
title = {Synthesis of 2-(buta-1,3-diynyl)-N,N-dimethylanilines Using Reductive Methylation Step},
journal = {Mendeleev Communications},
year = {2014},
volume = {24},
publisher = {Mendeleev Communications},
month = {Feb},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2014.03.013},
number = {2},
pages = {102--104},
doi = {10.1016/j.mencom.2014.03.013}
}
MLA
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Kulyashova, Alexandra Evgenievna, et al. “Synthesis of 2-(buta-1,3-diynyl)-N,N-dimethylanilines Using Reductive Methylation Step.” Mendeleev Communications, vol. 24, no. 2, Feb. 2014, pp. 102-104. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2014.03.013.

Abstract

Synthesis of 2-(buta-1,3-diynyl)-N,N-dimethylanilines based on reductive methylation of ortho-iodoanilines using CH2O–NaBH3CN and coupling with terminal diacetylens was developed. Altered sequence including dimethylation of 2-(buta-1,3-diynyl)anilines was also successfully achieved and gave higher overall yields in the case of anilines without acceptor substituent in the ring.

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