Home / Publications / Unexpected formation of 4-alkyl-5-(4-alkylthiosemicarbazido)-4,5-dihydro-1,2,4-triazine-3(2H)-thiones from 1,3-dialkyl-4,5-bis-(4-alkylthiosemicarbazido)imidazolidin-2-ones in acidic medium

Unexpected formation of 4-alkyl-5-(4-alkylthiosemicarbazido)-4,5-dihydro-1,2,4-triazine-3(2H)-thiones from 1,3-dialkyl-4,5-bis-(4-alkylthiosemicarbazido)imidazolidin-2-ones in acidic medium

Galina Anatol'evna Gazieva 1
Galina Anatol'evna Gazieva
Pavel Aleksandrovich Poluboyarov 1
Pavel Aleksandrovich Poluboyarov
Natal'ya Georgievna Kolotyrkina 1
Natal'ya Georgievna Kolotyrkina
Elena Davidovna Lubuzh 1
Elena Davidovna Lubuzh
Angelina Nikolaevna Kravchenko 1
Angelina Nikolaevna Kravchenko
Published 2013-12-12
CommunicationVolume 24, Issue 1, 42-44
5
Share
Cite this
GOST
 | 
Cite this
GOST Copy
Gazieva G. A. et al. Unexpected formation of 4-alkyl-5-(4-alkylthiosemicarbazido)-4,5-dihydro-1,2,4-triazine-3(2H)-thiones from 1,3-dialkyl-4,5-bis-(4-alkylthiosemicarbazido)imidazolidin-2-ones in acidic medium // Mendeleev Communications. 2013. Vol. 24. No. 1. pp. 42-44.
GOST all authors (up to 50) Copy
Gazieva G. A., Poluboyarov P. A., Kolotyrkina N. G., Lubuzh E. D., Kravchenko A. N. Unexpected formation of 4-alkyl-5-(4-alkylthiosemicarbazido)-4,5-dihydro-1,2,4-triazine-3(2H)-thiones from 1,3-dialkyl-4,5-bis-(4-alkylthiosemicarbazido)imidazolidin-2-ones in acidic medium // Mendeleev Communications. 2013. Vol. 24. No. 1. pp. 42-44.
RIS
 | 
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.mencom.2013.12.014
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.12.014
TI - Unexpected formation of 4-alkyl-5-(4-alkylthiosemicarbazido)-4,5-dihydro-1,2,4-triazine-3(2H)-thiones from 1,3-dialkyl-4,5-bis-(4-alkylthiosemicarbazido)imidazolidin-2-ones in acidic medium
T2 - Mendeleev Communications
AU - Gazieva, Galina Anatol'evna
AU - Poluboyarov, Pavel Aleksandrovich
AU - Kolotyrkina, Natal'ya Georgievna
AU - Lubuzh, Elena Davidovna
AU - Kravchenko, Angelina Nikolaevna
PY - 2013
DA - 2013/12/12
PB - Mendeleev Communications
SP - 42-44
IS - 1
VL - 24
ER -
BibTex
 | 
Cite this
BibTex (up to 50 authors) Copy
@article{2013_Gazieva,
author = {Galina Anatol'evna Gazieva and Pavel Aleksandrovich Poluboyarov and Natal'ya Georgievna Kolotyrkina and Elena Davidovna Lubuzh and Angelina Nikolaevna Kravchenko},
title = {Unexpected formation of 4-alkyl-5-(4-alkylthiosemicarbazido)-4,5-dihydro-1,2,4-triazine-3(2H)-thiones from 1,3-dialkyl-4,5-bis-(4-alkylthiosemicarbazido)imidazolidin-2-ones in acidic medium},
journal = {Mendeleev Communications},
year = {2013},
volume = {24},
publisher = {Mendeleev Communications},
month = {Dec},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.12.014},
number = {1},
pages = {42--44},
doi = {10.1016/j.mencom.2013.12.014}
}
MLA
Cite this
MLA Copy
Gazieva, Galina Anatol'evna, et al. “Unexpected formation of 4-alkyl-5-(4-alkylthiosemicarbazido)-4,5-dihydro-1,2,4-triazine-3(2H)-thiones from 1,3-dialkyl-4,5-bis-(4-alkylthiosemicarbazido)imidazolidin-2-ones in acidic medium.” Mendeleev Communications, vol. 24, no. 1, Dec. 2013, pp. 42-44. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.12.014.

Abstract

4-Alkyl-5-(4-alkylthiosemicarbazido)-4,5-dihydro-1,2,4-triazine-3(2H)-thiones are obtained either by heating 1,3-dialkyl-4,5-bis-(4-alkylthiosemicarbazido)imidazolidin-2-ones in acidic medium or the reaction of 1,3-dialkyl-4,5-dihydroxyimidazolidin-2-ones with 4-methylthiosemicarbazide.

References

3.
Novel thiosemicarbazone derivatives as potential antitumor agents: Synthesis, physicochemical and structural properties, DNA interactions and antiproliferative activity
Đilović I., Rubčić M., Vrdoljak V., Pavelić S.K., Kralj M., Piantanida I., Cindrić M.
Bioorganic and Medicinal Chemistry, 2008
4.
A Series of α-Heterocyclic Carboxaldehyde Thiosemicarbazones Inhibit Topoisomerase IIα Catalytic Activity
Huang H., Chen Q., Ku X., Meng L., Lin L., Wang X., Zhu C., Wang Y., Chen Z., Li M., Jiang H., Chen K., Ding J., Liu H.
Journal of Medicinal Chemistry, 2010
5.
Synthesis and Antimicrobial Properties of New Thiosemicarbazide, 1,2,4-Triazole, and 1,3,4-Thiadiazole Derivatives of Sulfanylacetic Acid
Popiołek Ł., Kosikowska U., Dobosz M., Malm A.
Phosphorus, Sulfur and Silicon and the Related Elements, 2012
6.
Synthesis and antimicrobial activity of o- and p-hydroxybenzoic acid thiosemicarbazides
Nurkenov O.A., Satpaeva Z.B., Kulakov I.V., Akhmetova S.B., Zhaugasheva S.K.
Russian Journal of General Chemistry, 2012
7.
Synthesis of thiosemicarbazone and 4-thiazolidinone derivatives and their in vitro anti-Toxoplasma gondii activity
Tenório R.P., Carvalho C.S., Pessanha C.S., de Lima J.G., de Faria A.R., Alves A.J., de Melo E.J., Góes A.J.
Bioorganic and Medicinal Chemistry Letters, 2005
9.
Synthesis and antimalarial activity of semicarbazone and thiosemicarbazone derivatives
de Oliveira R.B., de Souza-Fagundes E.M., Soares R.P., Andrade A.A., Krettli A.U., Zani C.L.
European Journal of Medicinal Chemistry, 2008
10.
Docking and Database Screening Reveal New Classes of Plasmodium falciparum Dihydrofolate Reductase Inhibitors
Rastelli G., Pacchioni S., Sirawaraporn W., Sirawaraporn R., Parenti M.D., Ferrari A.M.
Journal of Medicinal Chemistry, 2003
11.
α-Ureidoalkylation of thiosemicarbazide and aminoguanidine
Sigachev A.S., Kravchenko A.N., Belyakov P.A., Lebedev O.V., Makhova N.N.
Russian Chemical Bulletin, 2006
12.
Gazieva G.A., Vasilevskii S.V., Belyakov P.A., Nelyubina Y.V., Lubuzh E.D., Kravchenko A.N.
Mendeleev Communications, 2010
13.
A novel synthesis of thioglycolurils by ring contraction of 5,7-dialkyl-3-thioxoperhydroimidazo[4,5- e ]-1,2,4-triazin-6-ones
Gazieva G., Poluboyarov P., Popov L., Kolotyrkina N., Kravchenko A., Makhova N.
Synthesis, 2012
14.
α-Thioureidoalkylation of urea heteroanalogs
Gazieva G._., Nelyubina Y.V., Kravchenko A.N., Sigachev A.S., Glukhov I.V., Struchkova M.I., Lyssenko K.A., Makhova N.N.
Russian Chemical Bulletin, 2009
15.
α-Thioureidoalkylation of 4-alkyl- and 4-phenylthiosemicarbazides
Gazieva G.A., Struchkova M.I., Kolotyrkina N.G.
Chemistry of Heterocyclic Compounds, 2011
16.
Belyakov P.A., Kadentsev V.I., Chizhov A.O., Kolotyrkina N.G., Shashkov A.S., Ananikov V.P.
Mendeleev Communications, 2010