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Synthesis and biological activity of a novel water-soluble methano[60]fullerene tetracarboxylic derivative

Alexey Borisovich Kornev 1
Alexey Borisovich Kornev
, 
Aleksandr Sergeevich Peregudov 2
Aleksandr Sergeevich Peregudov
, 
Vyacheslav Mikhailovich Martynenko 1
Vyacheslav Mikhailovich Martynenko
, 
Galina V Guseva 1
Galina V Guseva
, 
Tatiana Evgen'evna Sashenkova 1
Tatiana Evgen'evna Sashenkova
, 
Alexander Yur'evich Rybkin 1
Alexander Yur'evich Rybkin
, 
Irina Igorevna Faingold 1
Irina Igorevna Faingold
,  , 
Raisa Alekseevna Kotelnikova 1
Raisa Alekseevna Kotelnikova
, 
Nina Petrovna Konovalova 1
Nina Petrovna Konovalova
, 
Jan Balzarini 3
Jan Balzarini
, 
10.1016/j.mencom.2013.11.006
Published 2013-10-30
Communication , Volume 23, Issue 6, 323-325
17
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Kornev A. B. et al. Synthesis and biological activity of a novel water-soluble methano[60]fullerene tetracarboxylic derivative // Mendeleev Communications. 2013. Vol. 23. No. 6. pp. 323-325.
GOST all authors (up to 50) Copy
Kornev A. B., Peregudov A. S., Martynenko V. M., Guseva G. V., Sashenkova T. E., Rybkin A. Y., Faingold I. I., Mishchenko D. V., Kotelnikova R. A., Konovalova N. P., Balzarini J., Troshin P. A. Synthesis and biological activity of a novel water-soluble methano[60]fullerene tetracarboxylic derivative // Mendeleev Communications. 2013. Vol. 23. No. 6. pp. 323-325.
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TY - JOUR
DO - 10.1016/j.mencom.2013.11.006
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.11.006
TI - Synthesis and biological activity of a novel water-soluble methano[60]fullerene tetracarboxylic derivative
T2 - Mendeleev Communications
AU - Kornev, Alexey Borisovich
AU - Peregudov, Aleksandr Sergeevich
AU - Martynenko, Vyacheslav Mikhailovich
AU - Guseva, Galina V
AU - Sashenkova, Tatiana Evgen'evna
AU - Rybkin, Alexander Yur'evich
AU - Faingold, Irina Igorevna
AU - Mishchenko, Denis Valeryevich
AU - Kotelnikova, Raisa Alekseevna
AU - Konovalova, Nina Petrovna
AU - Balzarini, Jan
AU - Troshin, Pavel Anatol'evich
PY - 2013
DA - 2013/10/30
PB - Mendeleev Communications
SP - 323-325
IS - 6
VL - 23
ER -
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@article{2013_Kornev,
author = {Alexey Borisovich Kornev and Aleksandr Sergeevich Peregudov and Vyacheslav Mikhailovich Martynenko and Galina V Guseva and Tatiana Evgen'evna Sashenkova and Alexander Yur'evich Rybkin and Irina Igorevna Faingold and Denis Valeryevich Mishchenko and Raisa Alekseevna Kotelnikova and Nina Petrovna Konovalova and Jan Balzarini and Pavel Anatol'evich Troshin},
title = {Synthesis and biological activity of a novel water-soluble methano[60]fullerene tetracarboxylic derivative},
journal = {Mendeleev Communications},
year = {2013},
volume = {23},
publisher = {Mendeleev Communications},
month = {Oct},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.11.006},
number = {6},
pages = {323--325},
doi = {10.1016/j.mencom.2013.11.006}
}
MLA
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Kornev, Alexey Borisovich, et al. “Synthesis and biological activity of a novel water-soluble methano[60]fullerene tetracarboxylic derivative.” Mendeleev Communications, vol. 23, no. 6, Oct. 2013, pp. 323-325. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.11.006.

Abstract

A reaction of 3,3’,4,4’-tetrakis(methoxycarbonyl)benzophenone tosylhydrazone with fullerene C60 was used to obtain a novel methano-[60]fullerene derivative bearing four carboxylic groups, whose sodium and potassium salts are water-soluble. The compound possesses antiviral and anticancer activity as well as pronounced antioxidant properties in combination with a low toxicity.

References

1.
Twenty Years of Promises: Fullerene in Medicinal Chemistry
Da Ros T.
The Mathematics and Topology of Fullerenes, 2008
2.
Khaybullin R.N., Strobykina I.Y., Gubskaya V.P., Fazleeva G.M., Latypov S.K., Kataev V.E.
Mendeleev Communications, 2011
3.
Fedorova N.E., Klimova R.R., Tulenev Y.A., Chichev E.V., Kornev A.B., Troshin P.A., Kushch A.A.
Mendeleev Communications, 2012
4.
Buckysomes: fullerene-based nanocarriers for hydrophobic molecule delivery.
Partha R., Mitchell L.R., Lyon J.L., Joshi P.P., Conyers J.L.
ACS Nano, 2008
5.
In vivo gene delivery by cationic tetraamino fullerene
Maeda-Mamiya R., Noiri E., Isobe H., Nakanishi W., Okamoto K., Doi K., Sugaya T., Izumi T., Homma T., Nakamura E.
Proceedings of the National Academy of Sciences of the United States of America, 2010
6.
Synthesis and evaluation of Bingel-Hirsch multiadducts of paramagnetic gadofullerene as potential magnetic resonance imaging contrast agents.
He R., Xing G., Wang X., Jiao Y., Zhao H., Yuan H., Wang S., Dong J., Lei H.
Journal of Nanoscience and Nanotechnology, 2013
7.
The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene.
Baati T., Bourasset F., Gharbi N., Njim L., Abderrabba M., Kerkeni A., Szwarc H., Moussa F.
Biomaterials, 2012
8.
A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice
Quick K.L., Ali S.S., Arch R., Xiong C., Wozniak D., Dugan L.L.
Neurobiology of Aging, 2008
9.
Tissue Sites of Uptake of14C-Labeled C60
Bullard-Dillard R., Creek K.E., Scrivens W.A., Tour J.M.
Bioorganic Chemistry, 1996
10.
Mayorova J.Y., Nikitenko S.L., Troshin P.A., Peregudova S.M., Peregudov A.S., Kaplunov M.G., Lyubovskaya R.N.
Mendeleev Communications, 2007
11.
Troshin P.A., Kornev A.B., Peregudov A.S., Peregudova S.M., Lyubovskaya R.N.
Mendeleev Communications, 2007
13.
Troshin P.A., Troshina O.A., Peregudova S.M., Yudanova E.I., Buyanovskaya A.G., Konarev D.V., Peregudov A.S., Lapshina A.N., Lyubovskaya R.N.
Mendeleev Communications, 2006
14.
Arbuzov chemistry with chlorofullerene C60Cl6: a powerful method for selective synthesis of highly functionalized [60]fullerene derivatives.
Yurkova A.A., Khakina E.A., Troyanov S.I., Chernyak A., Shmygleva L., Peregudov A.S., Martynenko V.M., Dobrovolskiy Y.A., Troshin P.A.
Chemical Communications, 2012
15.
Facile preparation of amine and amino acid adducts of [60]fullerene using chlorofullerene C60Cl6 as a precursor
Kornev A.B., Khakina E.A., Troyanov S.I., Kushch A.A., Peregudov A., Vasilchenko A., Deryabin D.G., Martynenko V.M., Troshin P.A.
Chemical Communications, 2012
16.
Synthesis and antiviral activity of highly water-soluble polycarboxylic derivatives of [70]fullerene
Kornev A.B., Peregudov A.S., Martynenko V.M., Balzarini J., Hoorelbeke B., Troshin P.A.
Chemical Communications, 2011
17.
Highly selective reactions of C60Cl6 with thiols for the synthesis of functionalized [60]fullerene derivatives.
Khakina E.A., Yurkova A.A., Peregudov A.S., Troyanov S.I., Trush V.V., Vovk A.I., Mumyatov A.V., Martynenko V.M., Balzarini J., Troshin P.A.
Chemical Communications, 2012
18.
A highly water-soluble dendro[60]fullerene
Brettreich M., Hirsch A.
Tetrahedron Letters, 1998
19.
Water-soluble malonic acid derivatives of C60 with a defined three-dimensional structure
Lamparth I., Hirsch A.
Journal of the Chemical Society Chemical Communications, 1994
20.
Preparation and Characterization of Fulleroid and Methanofullerene Derivatives
Hummelen J.C., Knight B.W., LePeq F., Wudl F., Yao J., Wilkins C.L.
Journal of Organic Chemistry, 1995
21.
Chlorofullerene C60Cl6: a precursor for straightforward preparation of highly water-soluble polycarboxylic fullerene derivatives active against HIV
Troshina O.A., Troshin P.A., Peregudov A.S., Kozlovskiy V.I., Balzarini J., Lyubovskaya R.N.
Organic and Biomolecular Chemistry, 2007
22.
D. Shuster, S. Wilson, A. Kirschner, R. Schinazi, S. Schlueter-Wirtz, P. Tharnish, T. Barnett, J. Ermolieff, J. Tang, M. Brettereich and A. Hirsch, Functionalized Fullerenes: Proceedings of the Electrochemical Society. of USA, 2000, p. 267.
23.
Free-radical mechanisms in tissue injury
Slater T.F.
Biochemical Journal, 1984
24.
Free radicals and cell chemiluminescence
Vladimirov Y.A., Proskurnina E.V.
Biochemistry (Moscow), 2009
25.
Chemiluminescence in solutions
Vasil'ev R.F.
Soviet Physics Uspekhi, 1967