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Spin hyperpolarization in NMR to address enzymatic processes in vivo

Igor Valentinovich Koptyug 1, 2
Igor Valentinovich Koptyug
10.1016/j.mencom.2013.11.001
Published 2013-10-30
Focus article , Volume 23, Issue 6, 299-312
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Koptyug I. V. Spin hyperpolarization in NMR to address enzymatic processes in vivo // Mendeleev Communications. 2013. Vol. 23. No. 6. pp. 299-312.
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Koptyug I. V. Spin hyperpolarization in NMR to address enzymatic processes in vivo // Mendeleev Communications. 2013. Vol. 23. No. 6. pp. 299-312.
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TY - JOUR
DO - 10.1016/j.mencom.2013.11.001
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.11.001
TI - Spin hyperpolarization in NMR to address enzymatic processes in vivo
T2 - Mendeleev Communications
AU - Koptyug, Igor Valentinovich
PY - 2013
DA - 2013/10/30
PB - Mendeleev Communications
SP - 299-312
IS - 6
VL - 23
ER -
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@article{2013_Koptyug,
author = {Igor Valentinovich Koptyug},
title = {Spin hyperpolarization in NMR to address enzymatic processes in vivo},
journal = {Mendeleev Communications},
year = {2013},
volume = {23},
publisher = {Mendeleev Communications},
month = {Oct},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.11.001},
number = {6},
pages = {299--312},
doi = {10.1016/j.mencom.2013.11.001}
}
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Koptyug, Igor Valentinovich. “Spin hyperpolarization in NMR to address enzymatic processes in vivo.” Mendeleev Communications, vol. 23, no. 6, Oct. 2013, pp. 299-312. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.11.001.
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Abstract

Magnetic resonance imaging and spectroscopy are powerful techniques but have a relatively low sensitivity. Signal enhancement in NMR and MRI by several orders of magnitude can be provided by the so-called hyperpolarization methods. Recent achievements in the development of the dissolution dynamic nuclear polarization technique and its use in the studies of enzymatic processes in vivo and in vitro and other applications are presented. Parahydrogen-induced polarization is also briefly discussed. Finally, recent progress in extending the lifetime of nuclear spin hyperpolarization beyond the relaxation limit is mentioned.

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