Home / Publications / Betulonic acid–peptide conjugates: synthesis and evaluation of anti-inflammatory activity

Betulonic acid–peptide conjugates: synthesis and evaluation of anti-inflammatory activity

Anastasiya Iosifovna Govdi 1
Anastasiya Iosifovna Govdi
, 
Sergey Franzevich Vasilevskii 1
Sergey Franzevich Vasilevskii
, 
Nadezhda Vladimirovna Sokolova 2
Nadezhda Vladimirovna Sokolova
, 
Irina Vasil'evna Sorokina 3
Irina Vasil'evna Sorokina
, 
Tatyana Genrikhovna Tolstikova 3
Tatyana Genrikhovna Tolstikova
, 
Valentin Georgievich Nenajdenko 2
Valentin Georgievich Nenajdenko
10.1016/j.mencom.2013.09.007
Published 2013-09-10
Communication , Volume 23, Issue 5, 260-261
21
Share
Cite this
GOST
 | 
Cite this
GOST Copy
Govdi A. I. et al. Betulonic acid–peptide conjugates: synthesis and evaluation of anti-inflammatory activity // Mendeleev Communications. 2013. Vol. 23. No. 5. pp. 260-261.
GOST all authors (up to 50) Copy
Govdi A. I., Vasilevskii S. F., Sokolova N. V., Sorokina I. V., Tolstikova T. G., Nenajdenko V. G. Betulonic acid–peptide conjugates: synthesis and evaluation of anti-inflammatory activity // Mendeleev Communications. 2013. Vol. 23. No. 5. pp. 260-261.
RIS
 | 
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.mencom.2013.09.007
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.09.007
TI - Betulonic acid–peptide conjugates: synthesis and evaluation of anti-inflammatory activity
T2 - Mendeleev Communications
AU - Govdi, Anastasiya Iosifovna
AU - Vasilevskii, Sergey Franzevich
AU - Sokolova, Nadezhda Vladimirovna
AU - Sorokina, Irina Vasil'evna
AU - Tolstikova, Tatyana Genrikhovna
AU - Nenajdenko, Valentin Georgievich
PY - 2013
DA - 2013/09/10
PB - Mendeleev Communications
SP - 260-261
IS - 5
VL - 23
ER -
BibTex
 | 
Cite this
BibTex (up to 50 authors) Copy
@article{2013_Govdi,
author = {Anastasiya Iosifovna Govdi and Sergey Franzevich Vasilevskii and Nadezhda Vladimirovna Sokolova and Irina Vasil'evna Sorokina and Tatyana Genrikhovna Tolstikova and Valentin Georgievich Nenajdenko},
title = {Betulonic acid–peptide conjugates: synthesis and evaluation of anti-inflammatory activity},
journal = {Mendeleev Communications},
year = {2013},
volume = {23},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.09.007},
number = {5},
pages = {260--261},
doi = {10.1016/j.mencom.2013.09.007}
}
MLA
Cite this
MLA Copy
Govdi, Anastasiya Iosifovna, et al. “Betulonic acid–peptide conjugates: synthesis and evaluation of anti-inflammatory activity.” Mendeleev Communications, vol. 23, no. 5, Sep. 2013, pp. 260-261. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.09.007.

Abstract

Cycloaddition of betulonic acid propargyl ester and azido-containing Boc-protected peptides afforded the corresponding 1,2,3-triazole- linked conjugates, whose anti-inflammatory properties were studied.

References

1.
Pharmacological activities of natural triterpenoids and their therapeutic implications
Dzubak P., Hajduch M., Vydra D., Hustova A., Kvasnica M., Biedermann D., Markova L., Urban M., Sarek J.
Natural Product Reports, 2006
2.
Biological activity and pharmacological prospects of lupane terpenoids: II. Semisynthetic lupane derivatives
Tolstikova T.G., Sorokina I.V., Tolstikov G.A., Tolstikov A.G., Flekhter O.B.
Russian Journal of Bioorganic Chemistry, 2006
3.
Synthesis, modification, and antimicrobial activity of the N-methylpiperazinyl amides of triterpenic acids
Kazakova O.B., Giniyatullina G.V., Tolstikov G.A., Medvedeva N.I., Utkina T.M., Kartashova O.L.
Russian Journal of Bioorganic Chemistry, 2010
4.
10.1016/j.mencom.2013.09.007_bib0020
Tolstikov
RF Patent, 2002
5.
Effect of nitrogen-containing derivatives of the plant triterpenes betulin and glycyrrhetic acid on the growth of MT-4, MOLT-4, CEM, and Hep G2 tumor cells
Shintyapina A.B., Shults E.E., Petrenko N.I., Uzenkova N.V., Tolstikov G.A., Pronkina N.V., Kozhevnikov V.S., Pokrovsky A.G.
Russian Journal of Bioorganic Chemistry, 2007
6.
http://www.molinspiration.com.
7.
Rapid access to new bioconjugates of betulonic acid via click chemistry
Vasilevsky S.F., Govdi A.I., Sorokina I.V., Tolstikova T.G., Baev D.S., Tolstikov G.A., Mamatuyk V.I., Alabugin I.V.
Bioorganic and Medicinal Chemistry Letters, 2011
8.
Design and synthesis of bile acid-peptide conjugates linked via triazole moiety
Sokolova N.V., Latyshev G.V., Lukashev N.V., Nenajdenko V.G.
Organic and Biomolecular Chemistry, 2011
9.
10.1016/j.mencom.2013.09.007_bib0045
Nenajdenko
Eur. J. Org. Chem., 1445
10.
Multicomponent Reactions with Isocyanides
Dömling A., Ugi I.
Angewandte Chemie - International Edition, 2000
12.
Isocyanoacetate Derivatives: Synthesis, Reactivity, and Application
Gulevich A.V., Zhdanko A.G., Orru R.V., Nenajdenko V.G.
Chemical Reviews, 2010
13.
Isocyanide Chemistry: Application in Synthesis and Materials Science, ed. V. G. Nenajdenko, Wiley-VCH, Weinheim, 2012.
14.
10.1016/j.mencom.2013.09.007_sbref0055a
Gulevich
Synlett, 2009
15.
Nonracemizable Isocyanoacetates for Multicomponent Reactions
Zhdanko A.G., Nenajdenko V.G.
Journal of Organic Chemistry, 2008
18.
The Ugi reaction with CF3-carbonyl compounds: effective synthesis of α-trifluoromethyl amino acid derivatives
Gulevich A.V., Shevchenko N.E., Balenkova E.S., Röschenthaler G., Nenajdenko V.G.
Tetrahedron, 2008
20.
Nenajdenko V.G., Gulevich A.V., Chernichenko K.Y., Sokolova N.V., Balenkova E.S.
Mendeleev Communications, 2011
21.
Multicomponent synthesis of artificial nucleases and their RNase and DNase activity
Gulevich A.V., Koroleva L.S., Morozova O.V., Bakhvalova V.N., Silnikov V.N., Nenajdenko V.G.
Beilstein Journal of Organic Chemistry, 2011
22.
1,3-Cycloaddition synthesis of 1,2,3-triazole conjugates of betulonic acid with peptides
Govdi A.I., Vasilevsky S.F., Nenajdenko V.G., Sokolova N.V., Tolstikov G.A.
Russian Chemical Bulletin, 2011
23.
Synthesis of peptide conjugates of mestranol by a 1,3-dipolar cycloaddition click reaction
Sokolova N.V., Nenajdenko V.G.
Chemistry of Heterocyclic Compounds, 2012
24.
10.1016/j.mencom.2013.09.007_sbref0060c
Sokolova
Synthesis, 2012
25.
Synthesis of CF3-containing tetrapeptide surrogates via Ugi reaction/dipolar cycloaddition sequence
Vorobyeva D.V., Sokolova N.V., Nenajdenko V.G., Peregudov A.S., Osipov S.N.
Tetrahedron, 2012
26.
10.1016/j.mencom.2013.09.007_sbref0060e
Sokolova
Synthesis, 2013
27.
Synthesis and testing of trifluoromethyl-containing phosphonate–peptide conjugates as inhibitors of serine hydrolases
Sokolova N.V., Nenajdenko V.G., Sokolov V.B., Serebryakova O.G., Makhaeva G.F.
Bioorganic and Medicinal Chemistry Letters, 2011