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Synthesis of 2-hydroxymalonamides from Carbamoylsilane and A-keto Carboxamides

Xiao Juan Chen 1
Xiao Juan Chen
, 
Jian Xin Chen 1
Jian Xin Chen
10.1016/j.mencom.2013.03.019
Published 2013-03-06
Communication , Volume 23, Issue 2, 106-107
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Chen X. J., Chen J. X. Synthesis of 2-hydroxymalonamides from Carbamoylsilane and A-keto Carboxamides // Mendeleev Communications. 2013. Vol. 23. No. 2. pp. 106-107.
GOST all authors (up to 50) Copy
Chen X. J., Chen J. X. Synthesis of 2-hydroxymalonamides from Carbamoylsilane and A-keto Carboxamides // Mendeleev Communications. 2013. Vol. 23. No. 2. pp. 106-107.
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TY - JOUR
DO - 10.1016/j.mencom.2013.03.019
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.03.019
TI - Synthesis of 2-hydroxymalonamides from Carbamoylsilane and A-keto Carboxamides
T2 - Mendeleev Communications
AU - Chen, Xiao Juan
AU - Chen, Jian Xin
PY - 2013
DA - 2013/03/06
PB - Mendeleev Communications
SP - 106-107
IS - 2
VL - 23
ER -
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@article{2013_Chen,
author = {Xiao Juan Chen and Jian Xin Chen},
title = {Synthesis of 2-hydroxymalonamides from Carbamoylsilane and A-keto Carboxamides},
journal = {Mendeleev Communications},
year = {2013},
volume = {23},
publisher = {Mendeleev Communications},
month = {Mar},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.03.019},
number = {2},
pages = {106--107},
doi = {10.1016/j.mencom.2013.03.019}
}
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Chen, Xiao Juan, and Jian Xin Chen. “Synthesis of 2-hydroxymalonamides from Carbamoylsilane and A-keto Carboxamides.” Mendeleev Communications, vol. 23, no. 2, Mar. 2013, pp. 106-107. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.03.019.

Keywords

α-hydroxy-α-carbamoylamide; carbamoylsilane; α-ketoamide

Abstract

Reaction between N,N-dimethylcarbamoylsilane and N,N-dimethyl-a-keto carboxamides affords 2-hydroxy-N,N,N’,N’-tetramethyl-2- R-malonamides in good yields.

References

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An efficient boric acid-mediated preparation of α-hydroxyamides
Sravan Kumar J., Jonnalagadda S.C., Mereddy V.R.
Tetrahedron Letters, 2010
7.
Synthesis of α-Ketoamides from a Carbamoylsilane and Acid Chlorides
Chen J., Cunico R.F.
Journal of Organic Chemistry, 2004