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Selective Reduction and Dehydrogenation of 6-Benzylideneoctahydropyrrolo[1,2-a]Pyrimidines and 5-Benzylidenehexahydropyrrolo[1,2-a]Imidazoles as New Approaches to N-(ω-Aminoalkyl)Pyrrolidines and Bicyclic Amidines

Konstantin Nikolaevich Shavrin 1
Konstantin Nikolaevich Shavrin
, 
Valentin Dmitrievich Gvozdev 1
Valentin Dmitrievich Gvozdev
, 
Oleg Matveevich Nefedov 1
Oleg Matveevich Nefedov
10.1016/j.mencom.2013.01.011
Published 2013-01-03
Communication , Volume 23, Issue 1, 31-33
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Shavrin K. N., Gvozdev V. D., Nefedov O. M. Selective Reduction and Dehydrogenation of 6-Benzylideneoctahydropyrrolo[1,2-a]Pyrimidines and 5-Benzylidenehexahydropyrrolo[1,2-a]Imidazoles as New Approaches to N-(ω-Aminoalkyl)Pyrrolidines and Bicyclic Amidines // Mendeleev Communications. 2013. Vol. 23. No. 1. pp. 31-33.
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Shavrin K. N., Gvozdev V. D., Nefedov O. M. Selective Reduction and Dehydrogenation of 6-Benzylideneoctahydropyrrolo[1,2-a]Pyrimidines and 5-Benzylidenehexahydropyrrolo[1,2-a]Imidazoles as New Approaches to N-(ω-Aminoalkyl)Pyrrolidines and Bicyclic Amidines // Mendeleev Communications. 2013. Vol. 23. No. 1. pp. 31-33.
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TY - JOUR
DO - 10.1016/j.mencom.2013.01.011
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.01.011
TI - Selective Reduction and Dehydrogenation of 6-Benzylideneoctahydropyrrolo[1,2-a]Pyrimidines and 5-Benzylidenehexahydropyrrolo[1,2-a]Imidazoles as New Approaches to N-(ω-Aminoalkyl)Pyrrolidines and Bicyclic Amidines
T2 - Mendeleev Communications
AU - Shavrin, Konstantin Nikolaevich
AU - Gvozdev, Valentin Dmitrievich
AU - Nefedov, Oleg Matveevich
PY - 2013
DA - 2013/01/03
PB - Mendeleev Communications
SP - 31-33
IS - 1
VL - 23
ER -
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@article{2013_Shavrin,
author = {Konstantin Nikolaevich Shavrin and Valentin Dmitrievich Gvozdev and Oleg Matveevich Nefedov},
title = {Selective Reduction and Dehydrogenation of 6-Benzylideneoctahydropyrrolo[1,2-a]Pyrimidines and 5-Benzylidenehexahydropyrrolo[1,2-a]Imidazoles as New Approaches to N-(ω-Aminoalkyl)Pyrrolidines and Bicyclic Amidines},
journal = {Mendeleev Communications},
year = {2013},
volume = {23},
publisher = {Mendeleev Communications},
month = {Jan},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.01.011},
number = {1},
pages = {31--33},
doi = {10.1016/j.mencom.2013.01.011}
}
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Cite this
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Shavrin, Konstantin Nikolaevich, et al. “Selective Reduction and Dehydrogenation of 6-Benzylideneoctahydropyrrolo[1,2-a]Pyrimidines and 5-Benzylidenehexahydropyrrolo[1,2-a]Imidazoles as New Approaches to N-(ω-Aminoalkyl)Pyrrolidines and Bicyclic Amidines.” Mendeleev Communications, vol. 23, no. 1, Jan. 2013, pp. 31-33. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2013.01.011.

Abstract

Sodium borohydride reduction of 6-benzylideneoctahydropyrrolo[1,2-a]pyrimidines and 5-benzylidenehexahydropyrrolo[1,2-a]imidazoles affords N-(w-aminoalkyl)pyrrolidines, whereas these substrates react with H2 or cyclohexene in the presence of catalytic amounts of Pd/C to give benzyl- or benzylidene-substituted bicyclic amidines, respectively.

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