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Mannich Synthesis of Acetylenic Amino Alcohols in Aqueous Ionic Liquids

Nina Ivanovna Simirskaya 1
Nina Ivanovna Simirskaya
, 
Nikolai V Ignat'ev 2
Nikolai V Ignat'ev
, 
Michael Schulte 2
Michael Schulte
, 
Sergei Grigorievich Zlotin 1
Sergei Grigorievich Zlotin
2 Ionic Liquid Research Laboratory, Merck KGaA, Darmstadt, Germany
10.1016/j.mencom.2012.11.013
Published 2012-11-07
Communication , Volume 22, Issue 6, 317-319
8
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Simirskaya N. I. et al. Mannich Synthesis of Acetylenic Amino Alcohols in Aqueous Ionic Liquids // Mendeleev Communications. 2012. Vol. 22. No. 6. pp. 317-319.
GOST all authors (up to 50) Copy
Simirskaya N. I., Ignat'ev N. V., Schulte M., Zlotin S. G. Mannich Synthesis of Acetylenic Amino Alcohols in Aqueous Ionic Liquids // Mendeleev Communications. 2012. Vol. 22. No. 6. pp. 317-319.
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TY - JOUR
DO - 10.1016/j.mencom.2012.11.013
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2012.11.013
TI - Mannich Synthesis of Acetylenic Amino Alcohols in Aqueous Ionic Liquids
T2 - Mendeleev Communications
AU - Simirskaya, Nina Ivanovna
AU - Ignat'ev, Nikolai V
AU - Schulte, Michael
AU - Zlotin, Sergei Grigorievich
PY - 2012
DA - 2012/11/07
PB - Mendeleev Communications
SP - 317-319
IS - 6
VL - 22
ER -
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@article{2012_Simirskaya,
author = {Nina Ivanovna Simirskaya and Nikolai V Ignat'ev and Michael Schulte and Sergei Grigorievich Zlotin},
title = {Mannich Synthesis of Acetylenic Amino Alcohols in Aqueous Ionic Liquids},
journal = {Mendeleev Communications},
year = {2012},
volume = {22},
publisher = {Mendeleev Communications},
month = {Nov},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2012.11.013},
number = {6},
pages = {317--319},
doi = {10.1016/j.mencom.2012.11.013}
}
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Simirskaya, Nina Ivanovna, et al. “Mannich Synthesis of Acetylenic Amino Alcohols in Aqueous Ionic Liquids.” Mendeleev Communications, vol. 22, no. 6, Nov. 2012, pp. 317-319. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2012.11.013.

Abstract

Terminal alkynols react with formaldehyde and secondary amines in aqueous ionic liquid [emim]HSO–4 in the presence of Cu(OAc) to afford the corresponding 1-(a-hydroxyalkyl)- or 1-(b-hydroxyalkyl)-2-(aminomethyl)acetylenes in better yields in comparison with the reaction in conventional organic solvents. The catalytic system can be easily recovered and recycled.

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