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Ionic Liquids-assisted Synthesis of 3,4-Dihydroisoquinolines by the Bishler–Napieralski Reaction

Margarita Alekseevna Epishina 1
Margarita Alekseevna Epishina
, 
Alexander Sergeyevich Kulikov 1
Alexander Sergeyevich Kulikov
, 
Marina Ivanovna Struchkova 1
Marina Ivanovna Struchkova
, 
Nikolai V Ignat'ev 2
Nikolai V Ignat'ev
, 
Michael Schulte 2
Michael Schulte
, 
Nina Nikolaevna Makhova 1
Nina Nikolaevna Makhova
2 Ionic Liquid Research Laboratory, Merck KGaA, Darmstadt, Germany
10.1016/j.mencom.2012.09.014
Published 2012-09-17
Communication , Volume 22, Issue 5, 267-269
6
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Epishina M. A. et al. Ionic Liquids-assisted Synthesis of 3,4-Dihydroisoquinolines by the Bishler–Napieralski Reaction // Mendeleev Communications. 2012. Vol. 22. No. 5. pp. 267-269.
GOST all authors (up to 50) Copy
Epishina M. A., Kulikov A. S., Struchkova M. I., Ignat'ev N. V., Schulte M., Makhova N. N. Ionic Liquids-assisted Synthesis of 3,4-Dihydroisoquinolines by the Bishler–Napieralski Reaction // Mendeleev Communications. 2012. Vol. 22. No. 5. pp. 267-269.
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TY - JOUR
DO - 10.1016/j.mencom.2012.09.014
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2012.09.014
TI - Ionic Liquids-assisted Synthesis of 3,4-Dihydroisoquinolines by the Bishler–Napieralski Reaction
T2 - Mendeleev Communications
AU - Epishina, Margarita Alekseevna
AU - Kulikov, Alexander Sergeyevich
AU - Struchkova, Marina Ivanovna
AU - Ignat'ev, Nikolai V
AU - Schulte, Michael
AU - Makhova, Nina Nikolaevna
PY - 2012
DA - 2012/09/17
PB - Mendeleev Communications
SP - 267-269
IS - 5
VL - 22
ER -
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@article{2012_Epishina,
author = {Margarita Alekseevna Epishina and Alexander Sergeyevich Kulikov and Marina Ivanovna Struchkova and Nikolai V Ignat'ev and Michael Schulte and Nina Nikolaevna Makhova},
title = {Ionic Liquids-assisted Synthesis of 3,4-Dihydroisoquinolines by the Bishler–Napieralski Reaction},
journal = {Mendeleev Communications},
year = {2012},
volume = {22},
publisher = {Mendeleev Communications},
month = {Sep},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2012.09.014},
number = {5},
pages = {267--269},
doi = {10.1016/j.mencom.2012.09.014}
}
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Epishina, Margarita Alekseevna, et al. “Ionic Liquids-assisted Synthesis of 3,4-Dihydroisoquinolines by the Bishler–Napieralski Reaction.” Mendeleev Communications, vol. 22, no. 5, Sep. 2012, pp. 267-269. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2012.09.014.

Abstract

The Bishler–Napieralski cyclodehydration of N-acyl-2-arylethylamines into the corresponding 3,4-dihydroisoquinolines with POCl3 as a dehydration reagent proceeds in ionic liquids under milder conditions and in higher yields.

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