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Synthesis of 5-alkyl-2-amino-1,3,4-thiadiazoles and α,ω-bis(2-amino-1,3,4-thiadiazol-5-yl)alkanes in ionic liquids

Margarita Alekseevna Epishina 1
Margarita Alekseevna Epishina
, 
Alexander Sergeyevich Kulikov 1
Alexander Sergeyevich Kulikov
, 
Nikolai V Ignat'ev 2
Nikolai V Ignat'ev
, 
Michael Schulte 2
Michael Schulte
, 
Nina Nikolaevna Makhova 1
Nina Nikolaevna Makhova
2 Ionic Liquid Research Laboratory, Merck KGaA, Darmstadt, Germany
10.1016/j.mencom.2011.11.013
Published 2011-11-10
Communication , Volume 21, Issue 6, 331-333
20
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Epishina M. A. et al. Synthesis of 5-alkyl-2-amino-1,3,4-thiadiazoles and α,ω-bis(2-amino-1,3,4-thiadiazol-5-yl)alkanes in ionic liquids // Mendeleev Communications. 2011. Vol. 21. No. 6. pp. 331-333.
GOST all authors (up to 50) Copy
Epishina M. A., Kulikov A. S., Ignat'ev N. V., Schulte M., Makhova N. N. Synthesis of 5-alkyl-2-amino-1,3,4-thiadiazoles and α,ω-bis(2-amino-1,3,4-thiadiazol-5-yl)alkanes in ionic liquids // Mendeleev Communications. 2011. Vol. 21. No. 6. pp. 331-333.
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TY - JOUR
DO - 10.1016/j.mencom.2011.11.013
UR - https://mendcomm.colab.ws/publications/10.1016/j.mencom.2011.11.013
TI - Synthesis of 5-alkyl-2-amino-1,3,4-thiadiazoles and α,ω-bis(2-amino-1,3,4-thiadiazol-5-yl)alkanes in ionic liquids
T2 - Mendeleev Communications
AU - Epishina, Margarita Alekseevna
AU - Kulikov, Alexander Sergeyevich
AU - Ignat'ev, Nikolai V
AU - Schulte, Michael
AU - Makhova, Nina Nikolaevna
PY - 2011
DA - 2011/11/10
PB - Mendeleev Communications
SP - 331-333
IS - 6
VL - 21
ER -
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@article{2011_Epishina,
author = {Margarita Alekseevna Epishina and Alexander Sergeyevich Kulikov and Nikolai V Ignat'ev and Michael Schulte and Nina Nikolaevna Makhova},
title = {Synthesis of 5-alkyl-2-amino-1,3,4-thiadiazoles and α,ω-bis(2-amino-1,3,4-thiadiazol-5-yl)alkanes in ionic liquids},
journal = {Mendeleev Communications},
year = {2011},
volume = {21},
publisher = {Mendeleev Communications},
month = {Nov},
url = {https://mendcomm.colab.ws/publications/10.1016/j.mencom.2011.11.013},
number = {6},
pages = {331--333},
doi = {10.1016/j.mencom.2011.11.013}
}
MLA
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Epishina, Margarita Alekseevna, et al. “Synthesis of 5-alkyl-2-amino-1,3,4-thiadiazoles and α,ω-bis(2-amino-1,3,4-thiadiazol-5-yl)alkanes in ionic liquids.” Mendeleev Communications, vol. 21, no. 6, Nov. 2011, pp. 331-333. https://mendcomm.colab.ws/publications/10.1016/j.mencom.2011.11.013.

Abstract

Reaction of thiosemicarbazide with carboxylic acids, including N-substituted amino acids, in ionic liquids with H2SO4 as a catalyst affords 5-R-2-amino-1,3,4-thiadiazoles. On using alkanedicarboxylic acids, α,ω-bis(2-amino-1,3,4,-thiadiazol-5-yl)alkanes were obtained.

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